Cyclophilin A (CYPA)
[Edit]PPIA; CyP-A; CYPH; Peptidylprolyl Isomerase A; Peptidyl-Prolyl Isomerase A; Peptidyl-prolyl cis-trans isomerase A; Cyclosporin A-binding protein
Cyclophilin A, also called Peptidyl-prolyl Isomerase A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis- and trans- proline residues critical for proper folding of proteins. Cyclophilin is also incorporated into many viruses, including HIV-1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA979Mu01 | Recombinant Cyclophilin A (CYPA) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA979Mu02 | Recombinant Cyclophilin A (CYPA) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA979Mu01 | Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. |
LAA979Mu71 | Biotin-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC. | |
LAA979Mu81 | FITC-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IF. | |
PAA979Mu02 | Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. | |
MAA979Mu21 | Monoclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. | |
CAA979Mi22 | Anti-Cyclophilin A (CYPA) Monoclonal Antibody | Loading Control of WB. | |
MAA979Mu22 | Monoclonal Antibody to Cyclophilin A (CYPA) | WB; IHC | |
Assay Kits | SEA979Mu | ELISA Kit for Cyclophilin A (CYPA) | Enzyme-linked immunosorbent assay for Antigen Detection. |
HEA979Mu | High Sensitive ELISA Kit for Cyclophilin A (CYPA) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
Organism species: Rhesus monkey (Simian)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA979Si01 | Recombinant Cyclophilin A (CYPA) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA979Si01 | Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. |
LAA979Si71 | Biotin-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Cyclophilin A (CYPA) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cyclophilin A (CYPA) | ELISA Kit Customized Service Offer |
Organism species: Sus scrofa; Porcine (Pig)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA979Po01 | Recombinant Cyclophilin A (CYPA) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA979Po01 | Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. |
LAA979Po71 | Biotin-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Cyclophilin A (CYPA) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cyclophilin A (CYPA) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA979Bo01 | Recombinant Cyclophilin A (CYPA) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA979Bo01 | Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. |
LAA979Bo71 | Biotin-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC. | |
LAA979Bo81 | FITC-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IF. | |
Assay Kits | n/a | CLIA Kit for Cyclophilin A (CYPA) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cyclophilin A (CYPA) | ELISA Kit Customized Service Offer |
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- , Submitted (DEC-2008) to UniProtKB
- , Submitted (NOV-2005) to UniProtKB
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