Editing RAB3 GTPase Activating Protein Subunit 2(RAB3GAP2)

Content that violates any copyrights will be deleted. The content must be verifiable. Work submitted to CLOUD-CLONE can be edited, used, and redistributed — by anyone — subject to certain terms and conditions.

Item Name
Abbreviation
Synonyms
CAS
HGNC
MGI
PubMed
RGD
UniProt
Wiki
Summary	Members of the RAB3 protein family are implicated in Ca(2+)-dependent exocytosis. RAB3GAP, which is involved in regulation of RAB3 activity, is a heterodimeric complex consisting a 130-kD catalytic subunit (RAB3GAP1) and a 150-kD noncatalytic subunit (RAB3GAP2). RAB3GAP2 contains 1,393 amino acids. Northern blot analysis detected a 7.5-kb transcript in all human tissues examined. Western blot analysis of subcellular fractionated rat brain detected p150 enriched in the synaptic soluble fraction.p150 did not show GAP activity, and the interaction between p150 and p130 did not alter the activity of p130 or the subcellular distribution of the 2 proteins.RT-PCR ELISA detected highest expression in brain, followed by kidney, ovary, and heart. Intermediate expression was detected in all other tissues examined.
Contacts	(Please send us your contacts, e.g.: email@google.com and your other information)
More advices
CheckCode