Editing Polyisoprenoid Diphosphate Phosphatase Type 1(PDP1)

Content that violates any copyrights will be deleted. The content must be verifiable. Work submitted to CLOUD-CLONE can be edited, used, and redistributed — by anyone — subject to certain terms and conditions.

Item Name
Abbreviation
Synonyms
CAS
HGNC
MGI
PubMed
RGD
UniProt
Wiki
Summary	PPAPDC2 contains 6 predicted membrane-spanning domains and 3 conserved lipid phosphate phosphatase motifs. RT-PCR detected expression in both human polymorphonuclear leukocytes and HEK293 cells. Dot-blot analysis of human tissues detected strong expression in pancreas, placenta, spleen, liver, kidney, colon, pituitary gland, and thymus, and moderate to low expression in duodenum, whole brain, stomach, esophagus, lung, testis, and heart. Semiquantitative RT-PCR detected PPAPDC2 expression in PMN leukocytes at 60% of levels in liver.PPAPDC2 activity was optimal at pH 7.0 and 8.0 and was independent of divalent cations. Thin-layer chromatography using C14-labeled substrates showed that PPAPDC2 catalyzed dephosphorylation of PSDP to presqualene monophosphate but not PSMP to presqualene alcohol.
Contacts	(Please send us your contacts, e.g.: email@google.com and your other information)
More advices
CheckCode