Editing IK Cytokine, Down Regulator Of HLA II(IK)

Content that violates any copyrights will be deleted. The content must be verifiable. Work submitted to CLOUD-CLONE can be edited, used, and redistributed — by anyone — subject to certain terms and conditions.

Item Name
Abbreviation
Synonyms
CAS
HGNC
MGI
PubMed
RGD
UniProt
Wiki
Summary	IK is in fact part of a larger gene encoding a 557-amino acid protein that is 98% identical to the mouse sequence and contains an extensive stretch of arg-glu-asp (RED) repeats. Notably, the codon usage in the RED repeat is varied, suggesting the sequence is not a result of repetitive duplication. RE repeats are found in atrophin-1, and RD repeats are found in RD. RED is expressed in both bacterial and mammalian cells as an 80-kD protein. Sequence analysis predicted and immunofluorescence analysis demonstrated that RED is localized to nuclear dots similar to the expression pattern of PML bodies; however, RED does not colocalize with PML or coilin (COIL) and appears to be sequestered from the nucleoplasm.
Contacts	(Please send us your contacts, e.g.: email@google.com and your other information)
More advices
CheckCode