Editing Preferentially Expressed Antigen Of Melanoma Family Member 12(PRAMEF12)

Content that violates any copyrights will be deleted. The content must be verifiable. Work submitted to CLOUD-CLONE can be edited, used, and redistributed — by anyone — subject to certain terms and conditions.

Item Name
Abbreviation
Synonyms
CAS
HGNC
MGI
PubMed
RGD
UniProt
Wiki
Summary	Several tumor-associated antigen families, such as MAGE, GAGE, PRAME and BAGE, are of particular interest in tumor immunology because their expression, with exception of testis and fetal tissues, seems to be restricted to tumor cells. PRAMEF12 is a 483 amino acid protein containing three LRR (leucine-rich) repeats and is a member of the PRAME family. PRAMEF12 has homology to a melanoma-associated protein, PRAME. PRAME is a melanoma antigen recognized by cytotoxic T cells (CTLs) and is expressed in a variety of cancer cells, including leukemic cells. The PRAME gene is expressed at a high level in a very large fraction of tumors, such as melanomas, non small-cell lung carcinomas, sarcomas, head and neck tumors and renal carcinomas.
Contacts	(Please send us your contacts, e.g.: email@google.com and your other information)
More advices
CheckCode