Editing Zyg11 Homolog A(ZYG11A)

Content that violates any copyrights will be deleted. The content must be verifiable. Work submitted to CLOUD-CLONE can be edited, used, and redistributed — by anyone — subject to certain terms and conditions.

Item Name
Abbreviation
Synonyms
CAS
HGNC
MGI
PubMed
RGD
UniProt
Wiki
Summary	Zyg-11 and the cullin cul-2 promote the metaphase-to-anaphase transition and M phase exit at meiosis II in Caenorhabditis elegans. ZYG-11 acts with a CUL-2-based E3 ligase that is essential at meiosis II and that functions redundantly with the anaphase-promoting complex/cyclosome at meiosis I. PAR proteins and P granules become polarized in an inverted manner during the meiosis II delay resulting from zyg-11 or cul-2 inactivation, and that zyg-11 and cul-2 can regulate polarity establishment independently of a role in cell cycle progression. Microtubules appear dispensable for ectopic polarity during the meiosis II delay in zyg-11(RNAi) embryos, as well as for AP polarity during the first mitotic cell cycle in wild-type embryos.
Contacts	(Please send us your contacts, e.g.: email@google.com and your other information)
More advices
CheckCode