Cytokines and health in higher animals

Cytokines are a kind of low molecular weight soluble proteins which are formed in process of evolution for higher animals. They have many functions, such as regulation of innate immunity, adaptive immunity, blood cell formation, cell growth, tissue repair and so on. The types of cytokines which have been found recently are more than 100. According to the different functions, they can be divided into interleukin (IL), interferon (IFN), colony stimulating factor (CSF), tumor necrosis factor (TNF), erythropoietin (EPO) and other types. With the in-depth study, the total number of cytokines are changing and increasing year by year.

Cytokines are produced by specific cells and secreted into the animal's internal circulation system in vivo. They will be transported to the area of target cells by blood circulation, lymph circulation and so on, and they can combine with surface receptor of target cell in order to transfer information. There will be a series of physiological and biochemical changes for the target cells, which can regulate the immune system, hematopoietic system, nervous system and endocrine system, and play an important role in the process of cell proliferation, cell differentiation, cell interaction and so on. Therefore, it has very important theoretical and practical significance for studying the cytokine, and it will help us to elucidate the molecular mechanism of the regulation of immune, and provide a solid theoretical basis for using recombinant cytokines in the treatment of tumor, infection, inflammation, hematopoietic dysfunction and other diseases. It has a very broad application and market prospects.

Cloud-Clone Corp. is committed to the development of cytokine detection technology and related products. At present, we have owned about 270 kinds of ELISA kits for detection of cytokines which had basically covered all the reported cytokines, and in addition, conventional ELISA kits for human, rats, mice, pigs, cattle, chickens and other species can be chose. Users include GSK, Roche, Thermo-Fisher, Pfizer, Harvard University, Yale University and other scientific research and educational institutions in the world, and it has been published 1000+ high level papers including Nature, Cell, etc. by using our cytokine products (please see attachment for details).   

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