Top-Ranked ELISA Kits (TGFb1). Vol.1 (2019)

TGFb1 belongs to the TGF-βfamily, the highest proportion (>90%), and the most active multi-functional cell activity regulator. TGFb1 is a strong growth inhibitory factor in multicellular organisms, which can significantly inhibit the growth and proliferation of lymphocytes, hematopoietic stem cells, epithelial cells, endothelial cells, hepatocytes, keratinocytes and adipocytes, but TGFb1 can promote fibroblast proliferation, extracellular matrix protein expression, and bone matrix protein synthesis.

At present, TGFb1 is considered to be a tumor suppressor gene, and its defect in expression or activation can cause its growth inhibition to disappear, resulting in cell nausea. Clinical data indicate that TGFb1 has an important association with the development of cancers such as prostate cancer, breast cancer and rectal cancer. Therefore, accurate determination of TGFb1 content in samples is of great significance for the study of related cancers and other related diseases.