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Astrocytes Control Sensory Acuity via Tonic Inhibition in the Thalamus
On September 8, 2020, professor Justin Lee from Korea University of Science and Technology coauthered with Eunji Cheong from Yonsei University published a paper on Neuron. The paper titled Astrocytes Control Sensory Acuity via Tonic Inhibition in the Thalamus.The Polyclonal antibody (Putrescine, PAX051Ge01) of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaserchers.Sensory discrimination is essential for survival. However, how sensory information is finely controlled in the brain is not well defined. Here, we show that astrocytes control tactile acuity via tonic inhibition in the thalamus. Mechanistically, diamine oxidase (DAO) and the subsequent a......
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Literature of Cloud Clone products in Sep. 2020 (Excerpt)
In Sep. 2020, Literature of Cloud Clone products has exceeded 260. Cloud-Clone could provide multipleproteins, antibodies and ELISA kit, which has been praised by customers.
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ZIF-8 Modified Multifunctional Bone-Adhesive Hydrogels Promoting Angiogenesis and Osteogenesis for Bone Regeneration
On August 19, 2020, professor Junyu Chen and Qianbing Wan from Sichuan University West China Hospital of Stomatology published a paper on ACS Applied Materials & Interfaces. The paper titled ZIF-8 Modified Multifunctional Bone-Adhesive Hydrogels Promoting Angiogenesis and Osteogenesis for Bone Regeneration.The ELISA kit (COL1, SEA571Ra; VEGF-A, SEA143Ra) of Cloud-Clone brand was chosed to determine the concentation of COL1 and VEGF-A in this article, we are so proud for supporting the reaserchers.Designing bone adhesives with adhesiveness, antideformation, biocompatibility, and biofunctional effects has great practical significance for bone defect reconstructive treatment, especially f......
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Mechanically induced formation and maturation of 3D-matrix adhesions (3DMAs) in human mesenchymal stem cells
On August 12, 2020, professor Barbara Pui Chan from The University of Hong Kong published a paper on Biomaterials. The paper titled Mechanically induced formation and maturation of 3D-matrix adhesions (3DMAs) in human mesenchymal stem cells.The ELISA kit (ITGaV, SEB282Hu) of Cloud-Clone brand was chosed to determine the concentation of ITGaV in this article, we are so proud for supporting the reaserchersMechanical signal is important for regulating stem cell fate, but the molecular mechanisms involved are unclear. Cell-matrix adhesions are important molecular mechanosensors that their formation and maturation are force-dependent processes. However, most studies focused on the role of......
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Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13
On August 17, 2020, professor Lino Ferreira from University of Coimbra published a paper titled Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13 on Nature communications.The ELISA kit (MMP13, SEA099Mu) of Cloud-Clone brand was chosed to determine the concentation of MMP13 in this article, we are so proud for supporting the reaserchers.Hutchinson-Gilford Progeria Syndrome (HGPS) is a premature aging disease in children that leads to early death. Smooth muscle cells (SMCs) are the most affected cells in HGPS individuals, although the reason for such vulnerability remains poorly understood. In this work, we develop a microfluidic chip formed by ......
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NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye
On July 19, 2020, professor Wei Chi from Zhongshan Ophthalmic Center of Sun Yat-sen University published a paper on The Ocular Surface. The paper titled NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye.The recombinant protein kit (GSDMD, RPE529Mu01) of Cloud-Clone brand was chosed to rescue GSDMD KO mice in this article, we are so proud for supporting the reaserchers.Dry eye disease (DED) is a common and multifactor-induced autoimmune ocular surface disease. Environmental factors, such as desiccating stress (DS) and hyperosmolarity, affect the corneal epithelium to induce ocular surface inflammation in DED......