Endothelial protein C receptor (EPCR)
[Edit]CD201; PROCR; CCCA ;CCD41; BA42O4.2; EPCR; Endothelial Protein C Receptor; Cell Cycle, Centrosome-Associated Protein; Activated Protein C Receptor
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The endothelial cell protein C receptor (EPCR) functions as an important regulator of the protein C anticoagulant pathway by binding protein C and enhancing activation by the thrombin-thrombomodulin complex. EPCR binds to both protein C and activated protein C (APC) with high affinity.
A soluble form of EPCR (sEPCR) has recently been detected in normal rat plasma and has been shown to bind protein C and APC with an affinity similar to that of intact membrane-bound EPCR. In healthy individuals, sEPCR circulates at a concentration of 2.5 nM, a level that can increase up to 5-fold in patients with sepsis or systemic lupus erythematosus. In contrast to membrane-bound EPCR, sEPCR inhibits protein C activation over large vessel endothelium in culture.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA022Hu01 | Recombinant Endothelial protein C receptor (EPCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA022Hu02 | Active Endothelial protein C receptor (EPCR) | Cell culture; Activity Assays. | |
| Antibodies | PAA022Hu01 | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. |
| MAA022Hu22 | Monoclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. | |
| LAA022Hu71 | Biotin-Linked Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC. | |
| Assay Kits | SEA022Hu | ELISA Kit for Endothelial protein C receptor (EPCR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA022Mu01 | Recombinant Endothelial protein C receptor (EPCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA022Mu02 | Recombinant Endothelial protein C receptor (EPCR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA022Mu01 | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. |
| LAA022Mu71 | Biotin-Linked Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC. | |
| PAA022Mu02 | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA022Mu | ELISA Kit for Endothelial protein C receptor (EPCR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA022Ra01 | Recombinant Endothelial protein C receptor (EPCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA022Ra01 | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. |
| LAA022Ra71 | Biotin-Linked Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC. | |
| MAA022Ra21 | Monoclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA022Ra | ELISA Kit for Endothelial protein C receptor (EPCR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA022Po01 | Recombinant Endothelial protein C receptor (EPCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA022Po01 | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Endothelial protein C receptor (EPCR) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Endothelial protein C receptor (EPCR) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA022Bo01 | Recombinant Endothelial protein C receptor (EPCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA022Bo01 | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Endothelial protein C receptor (EPCR) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Endothelial protein C receptor (EPCR) | ELISA Kit Customized Service Offer |
Organism species: Ovis aries; Ovine (Sheep)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Endothelial protein C receptor (EPCR) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Endothelial protein C receptor (EPCR) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Endothelial protein C receptor (EPCR) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Endothelial protein C receptor (EPCR) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA022Ga01 | Recombinant Endothelial protein C receptor (EPCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA022Ga01 | Polyclonal Antibody to Endothelial protein C receptor (EPCR) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Endothelial protein C receptor (EPCR) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Endothelial protein C receptor (EPCR) | ELISA Kit Customized Service Offer |
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