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Chemokine C-C-Motif Receptor 8 (CCR8)

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CD198 ;CDw198; CKR-L1; CKRL1; CMKBR8; CMKBRL2; CY6; GPR-CY6; TER1; Chemokine, CC Motif, Receptor-Like 2; Chemokine Receptor-Like 1

Chemokine C-C-Motif Receptor 8 (CCR8)
CCC A023
HGNC 1609
MGI 1201402
PubMed 9207005
RGD 1304893
UniProt P51685
Wiki CCR8

Chemokine (C-C motif) receptor 8 is  a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. The ligand of the CCR8 is CCL1. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA023Hu01 Recombinant Chemokine C-C-Motif Receptor 8 (CCR8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA023Hu01 Polyclonal Antibody to Chemokine C-C-Motif Receptor 8 (CCR8) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Chemokine C-C-Motif Receptor 8 (CCR8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine C-C-Motif Receptor 8 (CCR8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chemokine C-C-Motif Receptor 8 (CCR8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chemokine C-C-Motif Receptor 8 (CCR8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chemokine C-C-Motif Receptor 8 (CCR8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chemokine C-C-Motif Receptor 8 (CCR8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine C-C-Motif Receptor 8 (CCR8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chemokine C-C-Motif Receptor 8 (CCR8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chemokine C-C-Motif Receptor 8 (CCR8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chemokine C-C-Motif Receptor 8 (CCR8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chemokine C-C-Motif Receptor 8 (CCR8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine C-C-Motif Receptor 8 (CCR8) ELISA Kit Customized Service Offer
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  2. "Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor."Eur. J. Immunol. 26:3021-3028(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309."J. Exp. Med. 186:165-170(1997) [PubMed] [Europe PMC] [Abstract]
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  9. "Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor."Eur. J. Immunol. 28:582-588(1998) [PubMed] [Europe PMC] [Abstract]
  10. "Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3."J. Immunol. 160:1975-1981(1998) [PubMed] [Europe PMC] [Abstract]
  11. "The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8."Eur. J. Immunol. 29:3210-3215(1999) [PubMed] [Europe PMC] [Abstract]