-90073.jpg)
Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen-activated T lymphocytes. IL-2 plays a key role in promoting the clonal expansion of antigen-specific T cells. In addition, IL-2 has also been shown to mediate multiple immune responses on a variety of cell types.
IL-2 stimulates the proliferation of thymocytes; stimulates the proliferation and differentiation of activated B cells; promotes the growth, differentiation and cytocidal activity of monocytes; induces the growth of and cytokine production and cytolytic activity by natural killer cells; enhances the production of lymphocyte-activated killer (LAK) cells; and induces the proliferation and differentiation of oligodendrocytes .
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Hu01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA073Hu61 | Eukaryotic Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA073Hu61 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| APA073Hu01 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| RPA073Hu02 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA073Hu02 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| Antibodies | PAA073Hu01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Hu22 | Monoclonal Antibody to Interleukin 2 (IL2) | WB | |
| LAA073Hu71 | Biotin-Linked Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC. | |
| PAA073Hu06 | Polyclonal Antibody to Interleukin 2 (IL2) | WB | |
| MAA073Hu21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Hu26 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Hu23 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Hu24 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Hu25 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Hu27 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Hu29 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Hu | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA073Hu | CLIA Kit for Interleukin 2 (IL2) | Chemiluminescent immunoassay for Antigen Detection. | |
| HEA073Hu | High Sensitive ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Mu01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA073Mu02 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA073Mu61 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| EPA073Mu61 | Eukaryotic Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA073Mu01 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| Antibodies | PAA073Mu01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| PAA073Mu02 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Mu21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Mu22 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Mu23 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Mu | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA073Mu | CLIA Kit for Interleukin 2 (IL2) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Ra01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA073Ra61 | Eukaryotic Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA073Ra61 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| Antibodies | LAA073Ra71 | Biotin-Linked Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC. |
| LAA073Ra81 | FITC-Linked Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IF. | |
| MAA073Ra21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| PAA073Ra01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| PAA073Ra06 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Ra26 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| LAA073Ra72 | Biotin-Linked Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC. | |
| Assay Kits | SEA073Ra | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA073Ra | CLIA Kit for Interleukin 2 (IL2) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Cavia (Guinea pig )
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Gu01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA073Gu01 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| Antibodies | PAA073Gu01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Gu21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Gu | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Rb01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPA073Rb21 | OVA Conjugated Interleukin 2 (IL2) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA073Rb51 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Rb21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| PAA073Rb58 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Rb | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rhesus monkey (Simian)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Si01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA073Si01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Si21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Si | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Ca01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA073Ca01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Ca21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Ca | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Po01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA073Po61 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| APA073Po01 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| Antibodies | PAA073Po01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Po21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Po22 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Po23 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| MAA073Po24 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Po | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Bo01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA073Bo01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Bo21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Bo | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Capra hircus; Caprine (Goat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Cp01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA073Cp01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Interleukin 2 (IL2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 2 (IL2) | ELISA Kit Customized Service Offer |
Organism species: Ovis aries; Ovine (Sheep)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Interleukin 2 (IL2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Interleukin 2 (IL2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interleukin 2 (IL2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEA073Ov | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Equus caballus; Equine (Horse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Eq01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA073Eq02 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA073Eq61 | Active Interleukin 2 (IL2) | Cell culture; Activity Assays. | |
| Antibodies | PAA073Eq01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| MAA073Eq21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA073Eq | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA073Ga01 | Recombinant Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA073Ga61 | Eukaryotic Interleukin 2 (IL2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA073Ga01 | Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. |
| LAA073Ga71 | Biotin-Linked Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC. | |
| LAA073Ga81 | FITC-Linked Polyclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IF. | |
| MAA073Ga21 | Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC; IP. | |
| LAA073Ga72 | Biotin-Linked Monoclonal Antibody to Interleukin 2 (IL2) | WB; IHC; ICC. | |
| Assay Kits | SEA073Ga | ELISA Kit for Interleukin 2 (IL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Cloning of interleukin 2 mRNAs from human tonsils."Biochem. Biophys. Res. Commun. 115:1040-1047(1983) [PubMed] [Europe PMC] [Abstract]
- "Structure and expression of a cloned cDNA for human interleukin-2."Nature 302:305-310(1983) [PubMed] [Europe PMC] [Abstract]
- "Molecular cloning of human interleukin 2 cDNA and its expression in E. coli."Nucleic Acids Res. 11:4307-4323(1983) [PubMed] [Europe PMC] [Abstract]
- "Structure of the human interleukin 2 gene."Proc. Natl. Acad. Sci. U.S.A. 80:7437-7441(1983) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence of the 5' flanking region of the human interleukin 2 gene: homologies with adult T-cell leukemia virus."Nucleic Acids Res. 12:5005-5013(1984) [PubMed] [Europe PMC] [Abstract]
- "T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells."Proc. Natl. Acad. Sci. U.S.A. 81:1634-1638(1984) [PubMed] [Europe PMC] [Abstract]
- "Interleukin-2 transcripts in human and rodent brains: possible expression by astrocytes."J. Neurochem. 64:1928-1936(1995) [PubMed] [Europe PMC] [Abstract]
- "Sequence of interleukin-2 isolated from human placental poly A+ RNA: possible role in maintenance of fetal allograft."Mol. Reprod. Dev. 43:180-186(1996) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Organization of the DNA regions flanking the human interleukin 2 gene."Biomed. Res. 6:197-205(1985)
- "Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells."Mol. Cell. Biol. 6:3042-3049(1986) [PubMed] [Europe PMC] [Abstract]
- "Structure-activity relationships of recombinant human interleukin 2."Biochemistry 27:6883-6892(1988) [PubMed] [Europe PMC] [Abstract]
- "Amino acid sequence and post-translational modification of human interleukin 2."Proc. Natl. Acad. Sci. U.S.A. 81:6486-6490(1984) [PubMed] [Europe PMC] [Abstract]
- "Expression of human interleukin-2 in recombinant baby hamster kidney, Ltk-, and Chinese hamster ovary cells. Structure of O-linked carbohydrate chains and their location within the polypeptide."J. Biol. Chem. 264:17368-17373(1989) [PubMed] [Europe PMC] [Abstract]
- "Three-dimensional structure of interleukin-2."Science 238:1707-1709(1987) [PubMed] [Europe PMC] [Abstract]
- "Unraveling the structure of IL-2."Science 257:410-412(1992) [PubMed] [Europe PMC] [Abstract]
- Science 257:412-413(1992)
- "Secondary structure of human interleukin 2 from 3D heteronuclear NMR experiments."Biochemistry 31:7741-7744(1992) [PubMed] [Europe PMC] [Abstract]
- "The interleukin-2 and interleukin-4 receptors studied by molecular modelling."Structure 2:839-851(1994) [PubMed] [Europe PMC] [Abstract]
- "Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors."Science 310:1159-1163(2005) [PubMed] [Europe PMC] [Abstract]
- "Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor."Proc. Natl. Acad. Sci. U.S.A. 103:2788-2793(2006) [PubMed] [Europe PMC] [Abstract]