Interleukin 3 (IL3)
[Edit]MCGF; MULTI-CSF; MCSF; M-CSF; Multiple; Multilineage-Colony-Stimulating Factor; Hematopoietic Growth Factor; P-Cell Stimulating Factor; Mast-Cell Growth Factor
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Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the Interleukin-3 receptor.
IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells as well as stimulates proliferation of all cells in the myeloid lineage (erythrocytes, thrombocytes, granulocytes, monocytes, and dendritic cells). It is secreted by activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. Interleukin-3 is a hematopoietic colony-stimulating factor that is capable of supporting the proliferation of a broad range of hematopoietic cell types. Interleukin-3 also has neurotrophic activity .
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA076Hu01 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA076Hu01 | Active Interleukin 3 (IL3) | Cell culture; Activity Assays. | |
| EPA076Hu61 | Eukaryotic Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA076Hu61 | Active Interleukin 3 (IL3) | Cell culture; Activity Assays. | |
| RPA076Hu02 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA076Hu01 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. |
| MAA076Hu22 | Monoclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. | |
| MAA076Hu21 | Monoclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA076Hu | ELISA Kit for Interleukin 3 (IL3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA076Mu01 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA076Mu02 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA076Mu61 | Active Interleukin 3 (IL3) | Cell culture; Activity Assays. | |
| EPA076Mu62 | Eukaryotic Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA076Mu01 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. |
| PAA076Mu02 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA076Mu | ELISA Kit for Interleukin 3 (IL3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA076Ra01 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA076Ra02 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| EPA076Ra61 | Eukaryotic Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA076Ra61 | Active Interleukin 3 (IL3) | Cell culture; Activity Assays. | |
| Antibodies | PAA076Ra01 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. |
| MAA076Ra21 | Monoclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. | |
| PAA076Ra02 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA076Ra | ELISA Kit for Interleukin 3 (IL3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA076Ca01 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA076Ca61 | Active Interleukin 3 (IL3) | Cell culture; Activity Assays. | |
| Antibodies | PAA076Ca01 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. |
| MAA076Ca21 | Monoclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA076Ca | ELISA Kit for Interleukin 3 (IL3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Interleukin 3 (IL3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Interleukin 3 (IL3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interleukin 3 (IL3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEA076Bo | ELISA Kit for Interleukin 3 (IL3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Capra hircus; Caprine (Goat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA076Cp01 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA076Cp01 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Interleukin 3 (IL3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 3 (IL3) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA076Ga01 | Recombinant Interleukin 3 (IL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA076Ga01 | Polyclonal Antibody to Interleukin 3 (IL3) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Interleukin 3 (IL3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 3 (IL3) | ELISA Kit Customized Service Offer |
- "Characterization of a human multilineage-colony-stimulating factor cDNA clone identified by a conserved noncoding sequence in mouse interleukin-3."Gene 55:115-124(1987) [PubMed] [Europe PMC] [Abstract]
- "Isolation and characterization of an expressible cDNA encoding human IL-3. Induction of IL-3 mRNA in human T cell clones."J. Immunol. 140:2288-2295(1988) [PubMed] [Europe PMC] [Abstract]
- "Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3."Cell 47:3-10(1986) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Molecular characterization of colony-stimulating factors and their receptors: human interleukin-3."Ann. N. Y. Acad. Sci. 554:167-176(1989) [PubMed] [Europe PMC] [Abstract]
- "Three-dimensional solution structure and backbone dynamics of a variant of human interleukin-3."J. Mol. Biol. 259:524-541(1996) [PubMed] [Europe PMC] [Abstract]