Interleukin 27A (IL27A)
[Edit]p28; IL30; Interleukin 30; Interleukin-27 subunit alpha; IL-27 subunit alpha; IL27-A
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Interleukin 27A, also called Interleukin-30 (IL-30), is a protein with a molecular weight of 28 kilodaltons, which forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus is sometimes called IL27-p28. The other chain of IL-27 is a molecule called Epstein-Barr induced gene-3 (EBI3).
IL-30 is a member of the long-chain, 4-helix bundle family of cytokines, making it structurally similar to IL-6. This gene for this molecule is now officially called IL-27 under HGNC guidelines. IL27 is produced by antigen-presenting cells, and it mainly functions in innate immunity.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA385Hu01 | Recombinant Interleukin 27A (IL27A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA385Hu01 | Active Interleukin 27A (IL27A) | Cell culture; Activity Assays. | |
| EPA385Hu61 | Eukaryotic Interleukin 27A (IL27A) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA385Hu01 | Polyclonal Antibody to Interleukin 27A (IL27A) | WB; IHC; ICC; IP. |
| MAA385Hu22 | Monoclonal Antibody to Interleukin 27A (IL27A) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA385Hu | ELISA Kit for Interleukin 27A (IL27A) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA385Mu01 | Recombinant Interleukin 27A (IL27A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA385Mu61 | Eukaryotic Interleukin 27A (IL27A) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA385Mu61 | Active Interleukin 27A (IL27A) | Cell culture; Activity Assays. | |
| Antibodies | PAA385Mu01 | Polyclonal Antibody to Interleukin 27A (IL27A) | WB; IHC; ICC; IP. |
| Assay Kits | SEA385Mu | ELISA Kit for Interleukin 27A (IL27A) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA385Ra01 | Recombinant Interleukin 27A (IL27A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA385Ra01 | Polyclonal Antibody to Interleukin 27A (IL27A) | WB; IHC; ICC; IP. |
| MAA385Ra21 | Monoclonal Antibody to Interleukin 27A (IL27A) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA385Ra | ELISA Kit for Interleukin 27A (IL27A) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Interleukin 27A (IL27A) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Interleukin 27A (IL27A) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interleukin 27A (IL27A) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Interleukin 27A (IL27A) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 27A (IL27A) | ELISA Kit Customized Service Offer |
- "IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells." Immunity 16:779-790(2002) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells."J. Interferon Cytokine Res. 23:513-522(2003) [PubMed] [Europe PMC] [Abstract]
- "Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27."Blood 109:1841-1849(2007) [PubMed] [Europe PMC] [Abstract]
- "Interleukin-27 upregulates major histocompatibility complex class II expression in primary human endothelial cells through induction of major histocompatibility complex class II transactivator."Hum. Immunol. 68:965-972(2007) [PubMed] [Europe PMC] [Abstract]
- "The biology and therapeutic potential of interleukin 27."J. Mol. Med. 85:661-672(2007) [PubMed] [Europe PMC] [Abstract]
- "Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population."J. Hum. Genet. 52:355-361(2007) [PubMed] [Europe PMC] [Abstract]