Sex Hormone Binding Globulin (SHBG)
[Edit]ABP; TEBG; SBP; Sex steroid-binding protein; Testis-specific androgen-binding protein; Testosterone-estradiol-binding globulin; Testosterone-estrogen-binding globulin
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SHBG is a glycoprotein that binds to sex hormones, specifically testosterone and estradiol. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin. These sex hormones circulate in the bloodstream, bound mostly to SHBG and to some degree bound to serum albumin. Only a small fraction is unbound, or "free," and thus biologically active and able to enter a cell and activate its receptor. The SHBG inhibits the function of these hormones. Thus bioavailability of sex hormones is influenced by the level of SHBG. SHBG is produced by the liver cells and is released into the bloodstream. Other sites that produce SHBG are the brain, uterus, and placenta and vagina. In addition SHBG is produced by the testes; testes-produced SHBG is also called androgen-binding protein.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA396Mu01 | Recombinant Sex Hormone Binding Globulin (SHBG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA396Mu02 | Recombinant Sex Hormone Binding Globulin (SHBG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA396Mu01 | Polyclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC; IP. |
| LAA396Mu71 | Biotin-Linked Polyclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC. | |
| PAA396Mu02 | Polyclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC; IP. | |
| MAA396Mu21 | Monoclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA396Mu | ELISA Kit for Sex Hormone Binding Globulin (SHBG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA396Ra01 | Recombinant Sex Hormone Binding Globulin (SHBG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA396Ra02 | Recombinant Sex Hormone Binding Globulin (SHBG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA396Ra01 | Polyclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC; IP. |
| LAA396Ra71 | Biotin-Linked Polyclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC. | |
| LAA396Ra81 | FITC-Linked Polyclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC; IF. | |
| MAA396Ra21 | Monoclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC; IP. | |
| PAA396Ra02 | Polyclonal Antibody to Sex Hormone Binding Globulin (SHBG) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA396Ra | ELISA Kit for Sex Hormone Binding Globulin (SHBG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- ErratumNat. Genet. 23:373-373(1999)