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High Mobility Group Protein 1 (HMGB1)

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HMG1; HMG3; SBP1; Sulfoglucuronyl Carbohydrate Binding Protein; Amphoterin; High Mobility Group Box 1 Protein

High Mobility Group Protein 1 (HMGB1)
CCC A399
HGNC 4983
MGI 96113
PubMed 10391216
RGD 2802
UniProt P09429
Wiki HMGB1

High Mobility Group Box 1 is a non-histone chomosomal protein that functions in endotoxin lethality. It is released from activated macrophages and is present at elevated levels in the serum of sepsis patients. HMGB1 was also reported to interact with RAGE (receptor for advanced glycation end products) and to influence neuron development.A large number of sequences related to the cDNA for HMG1 protein hampered the cloning and mapping of the active HMG1 gene. Ferrari et al. (1996) showed that the HMG1 gene contains introns, whereas the HMG1-related sequences do not and most likely are retrotransposed pseudogenes. They identified 8 YACs from the ICI and CEPH libraries that contain the human HMG1 gene. The gene is similar in structure to the previously characterized mouse homolog.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA399Hu01 Recombinant High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA399Hu02 Recombinant High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
EPA399Hu61 Eukaryotic High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
APA399Hu02 Active High Mobility Group Protein 1 (HMGB1) Cell culture; Activity Assays.
APA399Hu61 Active High Mobility Group Protein 1 (HMGB1) Cell culture; Activity Assays.
EPA399Hu62 Eukaryotic High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
EPA399Hu63 Eukaryotic High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
APA399Hu62 Active High Mobility Group Protein 1 (HMGB1) Cell culture; Activity Assays.
APA399Hu63 Active High Mobility Group Protein 1 (HMGB1) Cell culture; Activity Assays.
Antibodies PAA399Hu01 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Hu22 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB;ICC/IF
LAA399Hu71 Biotin-Linked Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC.
LAA399Hu81 FITC-Linked Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IF.
PAA399Hu02 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB,IHC
PAA399Hu06 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Hu21 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Hu23 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Hu24 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Hu25 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Hu27 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
Assay Kits SEA399Hu ELISA Kit for High Mobility Group Protein 1 (HMGB1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA399Hu CLIA Kit for High Mobility Group Protein 1 (HMGB1) Chemiluminescent immunoassay for Antigen Detection.
IEA399Hu Instant ELISA Kit for High Mobility Group Protein 1 (HMGB1) Enzyme-linked immunosorbent assay for Antigen Detection.
AEA399Hu ELISA Kit for Anti-High Mobility Group Protein 1 Antibody (Anti-HMGB1) Enzyme-linked immunosorbent assay for Antibody Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA399Mu01 Recombinant High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA399Mu02 Recombinant High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
APA399Mu02 Active High Mobility Group Protein 1 (HMGB1) Cell culture; Activity Assays.
EPA399Mu61 Eukaryotic High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA399Mu01 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB,IHC,ICC/IF
LAA399Mu71 Biotin-Linked Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC.
LAA399Mu81 FITC-Linked Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IF.
PAA399Mu02 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
Assay Kits SEA399Mu ELISA Kit for High Mobility Group Protein 1 (HMGB1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA399Ra01 Recombinant High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
APA399Ra01 Active High Mobility Group Protein 1 (HMGB1) Cell culture; Activity Assays.
Antibodies PAA399Ra01 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB,IHC
LAA399Ra71 Biotin-Linked Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC.
LAA399Ra81 FITC-Linked Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IF.
MAA399Ra21 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
Assay Kits SEA399Ra ELISA Kit for High Mobility Group Protein 1 (HMGB1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA399Ca01 Recombinant High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA399Ca01 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Ca21 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
Assay Kits SEA399Ca ELISA Kit for High Mobility Group Protein 1 (HMGB1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA399Po01 Recombinant High Mobility Group Protein 1 (HMGB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA399Po01 Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
MAA399Po21 Monoclonal Antibody to High Mobility Group Protein 1 (HMGB1) WB; IHC; ICC; IP.
Assay Kits SEA399Po ELISA Kit for High Mobility Group Protein 1 (HMGB1) Enzyme-linked immunosorbent assay for Antigen Detection.
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