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Mineralocorticoid Receptor (MR)

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NR3C2; MLR; MCR; Aldosterone Receptor; Nuclear Receptor Subfamily 3 Group C Member 2

Mineralocorticoid Receptor (MR)
CCC A464
HGNC 7979
MGI 99459
PubMed 15947887
RGD 3094
UniProt P08235
Wiki MR

The mineralocorticoid receptor  is a receptor with high affinity for mineralocorticoids. It belongs to the steroid hormone receptor family where the ligand diffuses into cells, interacts with the receptor and results in a signal transduction affecting specific gene expression in the nucleus. The gene for the NR3C2 encodes for the 107 kDa MR protein. MR is expressed in many tissues, such as the kidney, colon, heart, central nervous system (hippocampus), brown adipose tissue and sweat glands. In epithelial tissues, its activation leads to the expression of proteins regulating ionic and water transports resulting in the reabsoprtion of sodium, and as a consequence an increase in extracellular volume, increase in blood pressure, and an excretion of potassium to maintain a normal salt concentration in the body.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA464Hu01 Recombinant Mineralocorticoid Receptor (MR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA464Hu01 Polyclonal Antibody to Mineralocorticoid Receptor (MR) WB; IHC; ICC; IP.
MAA464Hu22 Monoclonal Antibody to Mineralocorticoid Receptor (MR) WB; IHC; ICC; IP.
Assay Kits SEA464Hu ELISA Kit for Mineralocorticoid Receptor (MR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mineralocorticoid Receptor (MR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mineralocorticoid Receptor (MR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mineralocorticoid Receptor (MR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mineralocorticoid Receptor (MR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mineralocorticoid Receptor (MR) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA464Ra01 Recombinant Mineralocorticoid Receptor (MR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA464Ra01 Polyclonal Antibody to Mineralocorticoid Receptor (MR) WB; IHC; ICC; IP.
MAA464Ra21 Monoclonal Antibody to Mineralocorticoid Receptor (MR) WB; IHC; ICC; IP.
Assay Kits SEA464Ra ELISA Kit for Mineralocorticoid Receptor (MR) Enzyme-linked immunosorbent assay for Antigen Detection.
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