Plasminogen Activator Inhibitor 2 (PAI2)
[Edit]SERPINB2; PLANH2; Serpin Peptidase Inhibitor Clade B Member 2; Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor
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Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that inactivates tPA and urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form.
It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy. The majority of expressed PAI-2 remains unsecreted due to the presence of an inefficient internal signal peptide.the intron-exon arrangement of PAI2 is identical to that of chicken ovalbumin and Y genes and distinct from that of other members of the serpin superfamily.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA531Hu01 | Recombinant Plasminogen Activator Inhibitor 2 (PAI2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA531Hu01 | Active Plasminogen Activator Inhibitor 2 (PAI2) | Cell culture; Activity Assays. | |
| EPA531Hu61 | Eukaryotic Plasminogen Activator Inhibitor 2 (PAI2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA531Hu61 | Active Plasminogen Activator Inhibitor 2 (PAI2) | Cell culture; Activity Assays. | |
| Antibodies | PAA531Hu01 | Polyclonal Antibody to Plasminogen Activator Inhibitor 2 (PAI2) | WB; IHC; ICC; IP. |
| MAA531Hu22 | Monoclonal Antibody to Plasminogen Activator Inhibitor 2 (PAI2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA531Hu | ELISA Kit for Plasminogen Activator Inhibitor 2 (PAI2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA531Hu | CLIA Kit for Plasminogen Activator Inhibitor 2 (PAI2) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA531Mu01 | Recombinant Plasminogen Activator Inhibitor 2 (PAI2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA531Mu02 | Recombinant Plasminogen Activator Inhibitor 2 (PAI2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| EPA531Mu61 | Eukaryotic Plasminogen Activator Inhibitor 2 (PAI2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA531Mu61 | Active Plasminogen Activator Inhibitor 2 (PAI2) | Cell culture; Activity Assays. | |
| Antibodies | PAA531Mu01 | Polyclonal Antibody to Plasminogen Activator Inhibitor 2 (PAI2) | WB; IHC; ICC; IP. |
| PAA531Mu02 | Polyclonal Antibody to Plasminogen Activator Inhibitor 2 (PAI2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA531Mu | ELISA Kit for Plasminogen Activator Inhibitor 2 (PAI2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA531Rb01 | Recombinant Plasminogen Activator Inhibitor 2 (PAI2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA531Rb51 | Polyclonal Antibody to Plasminogen Activator Inhibitor 2 (PAI2) | WB; IHC; ICC; IP. |
| MAA531Rb21 | Monoclonal Antibody to Plasminogen Activator Inhibitor 2 (PAI2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA531Rb | ELISA Kit for Plasminogen Activator Inhibitor 2 (PAI2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- ErratumNat. Genet. 23:373-373(1999)