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Chemokine C-X-C-Motif Receptor 3 (CXCR3)

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CD183; CKR-L2; CMKAR3; GPR9; IP10r; IP10-R; Mig-R; MigR; G Protein-Coupled Receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor

Chemokine C-X-C-Motif Receptor 3 (CXCR3)
CCC A625
HGNC 4540
MGI 1277207
PubMed 9842912
RGD 621528
UniProt P49682
Wiki CXCR3

CD183 (CXCR3) is a multi-pass type-3, 7 span 368 aa glycoprotein.  It contains an extracellular domain which contains 3 potential amino-glycosylation sites, 7 putative transmembrane-spanning domains and an intracellular carboxyl-terminal regions which has 3 intracellular loop regions.  

The intracellular carboxyl-terminal region contains 10 Thr/Ser residues that may become phosphorylated during CD183-mediated signaling.  The DRYLAIVHA-motif in the 2nd intracellular loop is the most highly conserved sequence element in chemokine receptors.  CD183 is a chemokine receptor which are G-proteins coupled receptors.  CD183 shares a 30% identity with CD181 (CXCR1) and CD182 (CXCR2).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA625Hu01 Recombinant Chemokine C-X-C-Motif Receptor 3 (CXCR3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA625Hu01 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 3 (CXCR3) WB; IHC; ICC; IP.
MAA625Hu22 Monoclonal Antibody to Chemokine C-X-C-Motif Receptor 3 (CXCR3) WB; IHC; ICC; IP.
Assay Kits SEA625Hu ELISA Kit for Chemokine C-X-C-Motif Receptor 3 (CXCR3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA625Mu01 Recombinant Chemokine C-X-C-Motif Receptor 3 (CXCR3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA625Mu01 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 3 (CXCR3) WB; IHC; ICC; IP.
Assay Kits SEA625Mu ELISA Kit for Chemokine C-X-C-Motif Receptor 3 (CXCR3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA625Ra01 Recombinant Chemokine C-X-C-Motif Receptor 3 (CXCR3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA625Ra01 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 3 (CXCR3) WB; IHC; ICC; IP.
MAA625Ra21 Monoclonal Antibody to Chemokine C-X-C-Motif Receptor 3 (CXCR3) WB; IHC; ICC; IP.
Assay Kits SEA625Ra ELISA Kit for Chemokine C-X-C-Motif Receptor 3 (CXCR3) Enzyme-linked immunosorbent assay for Antigen Detection.
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