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Caspase 9 (CASP9)

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APAF3; ICE-LAP6; MCH6; Apoptosis-Related Cysteine Peptidase; Cysteinyl Aspartate Specific Proteinases 9; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6

Caspase 9 (CASP9)
CCC A627
HGNC 1511
MGI 1277950
PubMed 10687948
RGD 61867
UniProt P55211
Wiki Caspase-9

The aspartic acid specific protease caspase-9 has been linked to the mitochondrial death pathway. It is activated during programmed cell death (apoptosis). Induction of stress signalling pathways JNK/SAPK causes release of cytochrome c from mitochondria and activation of apaf-1 (apoptosome), which in turn cleaves the pro-enzyme of caspase-9 into the active form.

Caspase-9 is a member of the cysteine-aspartic acid protease (caspase) family. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA627Hu01 Recombinant Caspase 9 (CASP9) Positive Control; Immunogen; SDS-PAGE; WB.
RPA627Hu02 Recombinant Caspase 9 (CASP9) Positive Control; Immunogen; SDS-PAGE; WB.
RPA627Hu03 Recombinant Caspase 9 (CASP9) Positive Control; Immunogen; SDS-PAGE; WB.
RPA627Hu04 Recombinant Caspase 9 (CASP9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA627Hu01 Polyclonal Antibody to Caspase 9 (CASP9) WB; FCM
MAA627Hu22 Monoclonal Antibody to Caspase 9 (CASP9) WB,IHC
PAA627Hu02 Polyclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
LAA627Hu81 FITC-Linked Polyclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IF.
LAA627Hu71 Biotin-Linked Polyclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC.
PAA627Hu03 Polyclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
MAA627Hu23 Monoclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
MAA627Hu27 Monoclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
MAA627Hu29 Monoclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
MAA627Hu21 Monoclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
MAA627Hu24 Monoclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
MAA627Hu25 Monoclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
Assay Kits SEA627Hu ELISA Kit for Caspase 9 (CASP9) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA627Mu01 Recombinant Caspase 9 (CASP9) Positive Control; Immunogen; SDS-PAGE; WB.
RPA627Mu02 Recombinant Caspase 9 (CASP9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA627Mu01 Polyclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
PAA627Mu02 Polyclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
Assay Kits SEA627Mu ELISA Kit for Caspase 9 (CASP9) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA627Ra01 Recombinant Caspase 9 (CASP9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA627Ra01 Polyclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
MAA627Ra21 Monoclonal Antibody to Caspase 9 (CASP9) WB; IHC; ICC; IP.
Assay Kits SEA627Ra ELISA Kit for Caspase 9 (CASP9) Enzyme-linked immunosorbent assay for Antigen Detection.
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  19. "The E.coli effector protein NleF is a caspase inhibitor."PLoS ONE 0:0-0(2013)