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Cluster Of Differentiation 247 (CD247)

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CD3-ZETA; CD3H; CD3Q; CD3Z; TCRZ; TCR-Z; T-Cell Receptor Zeta; CD3z Antigen; Zeta Polypeptide TiT3 Complex; T-cell receptor T3 zeta chain

Cluster Of Differentiation 247 (CD247)
CCC A865
HGNC 1677
MGI 88334
PubMed 24343121
RGD 2305
UniProt P20963
Wiki CD247

T-cell receptor zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers and CD3-gamma, -delta, and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Comparison of the human and murine genes showed a high degree of conservation, including conservation in the nucleotide sequence of the 5-prime and 3-prime untranslated regions. No significant sequence and structural homology was found, however, with the previously characterized invariant delta, gamma, and epsilon chains of the T-cell receptor.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA865Hu01 Recombinant Cluster Of Differentiation 247 (CD247) Positive Control; Immunogen; SDS-PAGE; WB.
CPA865Hu21 OVA Conjugated Cluster Of Differentiation 247 (CD247) Immunogen; SDS-PAGE; WB.
Antibodies PAA865Hu08 Polyclonal Antibody to Cluster Of Differentiation 247 (CD247) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cluster Of Differentiation 247 (CD247) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cluster Of Differentiation 247 (CD247) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA865Mu01 Recombinant Cluster Of Differentiation 247 (CD247) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cluster Of Differentiation 247 (CD247) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cluster Of Differentiation 247 (CD247) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cluster Of Differentiation 247 (CD247) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cluster Of Differentiation 247 (CD247) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cluster Of Differentiation 247 (CD247) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cluster Of Differentiation 247 (CD247) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cluster Of Differentiation 247 (CD247) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cluster Of Differentiation 247 (CD247) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cluster Of Differentiation 247 (CD247) ELISA Kit Customized Service Offer
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  21. "Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45."J. Exp. Med. 201:441-452(2005) [PubMed] [Europe PMC] [Abstract]
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