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Protein Tyrosine Phosphatase Receptor Type M (PTPRM)

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PTPR-M; PTPRL1; R-PTP-MU; RPTPM; RPTPU; HR-PTPu; R-PTP-mu; Receptor-Type Tyrosine-Protein Phosphatase Mu

Protein Tyrosine Phosphatase Receptor Type M (PTPRM)
CCC A917
HGNC 9675
MGI 102694
PubMed 23185569
RGD 620776
UniProt P28827
Wiki PTPRM

Receptor-type tyrosine-protein phosphatase mu is a protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA917Hu01 Recombinant Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA917Hu01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type M (PTPRM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type M (PTPRM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type M (PTPRM) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type M (PTPRM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type M (PTPRM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type M (PTPRM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type M (PTPRM) ELISA Kit Customized Service Offer
  1. "Cloning, expression and chromosomal localization of a new putative receptor-like protein tyrosine phosphatase."FEBS Lett. 290:123-130(1991) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 18." Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "The crystal structure of domain 1 of receptor protein-tyrosine phosphatase mu."J. Biol. Chem. 272:27505-27508(1997) [PubMed] [Europe PMC] [Abstract]
  7. "Molecular analysis of receptor protein tyrosine phosphatase mu-mediated cell adhesion."EMBO J. 25:701-712(2006) [PubMed] [Europe PMC] [Abstract]