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Aldosterone Synthase (ALDOS)

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CPN2; CYP11B; CYP11BL; CYP11B2; P450C18; P450aldo; Steroid 18-hydroxylase; Aldosterone-synthesizing enzyme; Cytochrome P450 Family 11 Subfamily B Polypeptide 2

Aldosterone Synthase (ALDOS)
CCC A987
HGNC 2592
MGI 88583
PubMed 15134805
RGD 2454
UniProt P19099
Wiki ALDOS

Aldosterone synthase (or 18-hydroxylase) is a steroid hydroxylase cytochrome P450 oxidase enzyme involved in the generation of aldosterone. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein is primarily expressed in the zona glomerulosa of the adrenal cortex. Within the cell, it localizes to the inner membrane of the mitochondria. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA987Hu01 Recombinant Aldosterone Synthase (ALDOS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Aldosterone Synthase (ALDOS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aldosterone Synthase (ALDOS) Polyclonal Antibody Customized Service Offer
Assay Kits SEA987Hu ELISA Kit for Aldosterone Synthase (ALDOS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aldosterone Synthase (ALDOS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aldosterone Synthase (ALDOS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aldosterone Synthase (ALDOS) Polyclonal Antibody Customized Service Offer
Assay Kits SEA987Mu ELISA Kit for Aldosterone Synthase (ALDOS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA987Ra01 Recombinant Aldosterone Synthase (ALDOS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA987Ra01 Polyclonal Antibody to Aldosterone Synthase (ALDOS) WB; IHC; ICC; IP.
MAA987Ra21 Monoclonal Antibody to Aldosterone Synthase (ALDOS) WB; IHC; ICC; IP.
Assay Kits SEA987Ra ELISA Kit for Aldosterone Synthase (ALDOS) Enzyme-linked immunosorbent assay for Antigen Detection.
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