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S100 Calcium Binding Protein A12 (S100A12)

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CGRP; P6; CAAF1; CAGC; ENRAGE; MRP6; Calgranulin C; Calcium-binding protein in amniotic fluid 1; Extracellular newly identified RAGE-binding; Migration inhibitory factor-related 6

S100 Calcium Binding Protein A12 (S100A12)
CCC B080
HGNC 10489
PubMed 17414728
UniProt P80511
Wiki S100A12

S100A12 belongs to the S-100 (soluble in 100% saturated ammonium sulfate) family. Similar to other S100 proteins, S100A12 is small, it only has 91 amino acids, contains 2 EF-hand calcium-binding motifs and a Hinge domain. The hinge domain contributes significantly to its chemotactic properties. In the absence of divalent cations, S100A12 forms noncovalent homodimers; in the presence of calcium, zinc and copper ions, it forms tetramers or hexamers. S100A12 can interact with AGER and both calcium and zinc are essential for the interaction; it can Interact with CACYBP in a calcium-dependent manner. Besides, it can form heterodimers with S100A9. S100A12 plays a prominent role in the regulation of inflammatory processes and immune response. The concentration of S100A12 is high in the serum of patients suffering from various inflammatory disorders, including rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB080Hu01 Recombinant S100 Calcium Binding Protein A12 (S100A12) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB080Hu01 Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
MAB080Hu22 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
LAB080Hu71 Biotin-Linked Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC.
LAB080Hu81 FITC-Linked Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IF.
MAB080Hu21 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB
MAB080Hu23 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
MAB080Hu24 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB.
MAB080Hu29 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
MAB080Hu27 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
MAB080Hu25 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB,ICC/IF
MAB080Hu26 Monoclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
Assay Kits SEB080Hu ELISA Kit for S100 Calcium Binding Protein A12 (S100A12) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB080Rb01 Recombinant S100 Calcium Binding Protein A12 (S100A12) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB080Rb51 Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
PAB080Rb01 Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
Assay Kits SEB080Rb ELISA Kit for S100 Calcium Binding Protein A12 (S100A12) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB080Po01 Recombinant S100 Calcium Binding Protein A12 (S100A12) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB080Po01 Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
Assay Kits SEB080Po ELISA Kit for S100 Calcium Binding Protein A12 (S100A12) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB080Bo01 Recombinant S100 Calcium Binding Protein A12 (S100A12) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB080Bo01 Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12) WB; IHC; ICC; IP.
Assay Kits SEB080Bo ELISA Kit for S100 Calcium Binding Protein A12 (S100A12) Enzyme-linked immunosorbent assay for Antigen Detection.
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  20. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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