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Heat Shock 70kDa Protein 9 (HSPA9)

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CSA; GRP75; HSPA9B; MOT; MOT2; MTHSP75; PBP74; Mot-2; Stress-70 Protein,Mitochondrial; Mortalin,Perinuclear; 75 kDa glucose-regulated protein; Peptide-binding protein 74

Heat Shock 70kDa Protein 9 (HSPA9)
CCC B082
HGNC 5244
MGI 96245
PubMed 11187902
RGD 1311806
UniProt P38646
Wiki HSPA9
HSPA9contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.Mortal and immortal cells exhibit differential cellular localization of mortalin. All immortal human and mouse cells that have been tested are devoid of the uniformly distributed cytosolic form of the protein that is characteristic of normal cells. Senescent cultured cells were transiently induced to divide by the microinjection of anti-mortalin antibody. Expression of the cytosolic form (mot1) induced senescence of NIH 3T3 cells that normally harbor the perinuclear form (mot2), which differs from the cytosolic form by 2 amino acids.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB082Hu01 Recombinant Heat Shock 70kDa Protein 9 (HSPA9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB082Hu01 Polyclonal Antibody to Heat Shock 70kDa Protein 9 (HSPA9) WB; IHC
Assay Kits n/a CLIA Kit for Heat Shock 70kDa Protein 9 (HSPA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heat Shock 70kDa Protein 9 (HSPA9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heat Shock 70kDa Protein 9 (HSPA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heat Shock 70kDa Protein 9 (HSPA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heat Shock 70kDa Protein 9 (HSPA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heat Shock 70kDa Protein 9 (HSPA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heat Shock 70kDa Protein 9 (HSPA9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heat Shock 70kDa Protein 9 (HSPA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heat Shock 70kDa Protein 9 (HSPA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heat Shock 70kDa Protein 9 (HSPA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heat Shock 70kDa Protein 9 (HSPA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heat Shock 70kDa Protein 9 (HSPA9) ELISA Kit Customized Service Offer
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  9. , Submitted (DEC-2008) to UniProtKB
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  17. "Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux."Biochem. Biophys. Res. Commun. 433:322-326(2013) [PubMed] [Europe PMC] [Abstract]
  18. "Structural and stability studies of the human mtHsp70-escort protein 1: An essential mortalin co-chaperone."Int. J. Biol. Macromol. 56:140-148(2013) [PubMed] [Europe PMC] [Abstract]
  19. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]