≡

Nucleoporin 35kDa (NUP35)

[Edit]

MP44; NP44; Mitotic phosphoprotein 44; Nuclear pore complex protein Nup53

Nucleoporin 35kDa (NUP35)
CCC B087
HGNC 29797
MGI 1916732
PubMed 19146848
RGD 1303069
UniProt Q8NFH5
Wiki NUP35
Nucleoporin NUP53 is a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.MP44 has a calculated molecular mass of about 35 kD. It has a small number of scattered phenylalanine-glycine repeats, but not the large domains seen in other nucleoporins.
The central 150 amino acids of MP44 share 21% identity with S. cerevisiae Nup53.Fluorescence-tagged MP44, transfected into HeLa cells, showed punctate nuclear rim localization typical of nucleoporins. Based on this localization and the homology of MP44 to other nucleoporins, Cronshaw et al. (2002) proposed that MP44 be renamed NUP35.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB087Hu01 Recombinant Nucleoporin 35kDa (NUP35) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB087Hu01 Polyclonal Antibody to Nucleoporin 35kDa (NUP35) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Nucleoporin 35kDa (NUP35) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleoporin 35kDa (NUP35) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleoporin 35kDa (NUP35) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleoporin 35kDa (NUP35) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleoporin 35kDa (NUP35) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleoporin 35kDa (NUP35) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleoporin 35kDa (NUP35) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleoporin 35kDa (NUP35) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleoporin 35kDa (NUP35) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleoporin 35kDa (NUP35) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleoporin 35kDa (NUP35) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleoporin 35kDa (NUP35) ELISA Kit Customized Service Offer
  1. "Proteomic analysis of the mammalian nuclear pore complex."J. Cell Biol. 158:915-927(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex."Mol. Biol. Cell 16:2382-2394(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells."Mol. Cell 22:93-103(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]