Phospholipase A1 (PLA1)
[Edit]PLA1A; ps-PLA1; NMD; Phosphatidylserine-Specific Phospholipase A1-Alpha
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Phospholipase A1 is a phospholipase enzyme which removes the 1-acyl. Phospholipase A1 is a component of snake venom, but it also serves in normal metabolism to produce fatty acids from phospholipids. In melanocytic cells the Phospholipase A1 gene may be regulated by MITF.
Phosphatidylserine-specific phospholipase A1-alpha (PLA1A) acts specifically on phosphatidylserine (PS) and 1-acyl-2-lysophosphatidylserine (lyso-PS) to hydrolyze fatty acids at the sn-1 position of these phospholipids.Although PLA1A belongs to the phospholipase gene family, the predicted amino acid sequence of the rat gene product demonstrated greater homology with mammalian triglyceride lipases than with phospholipases.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB151Hu01 | Recombinant Phospholipase A1 (PLA1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB151Hu02 | Recombinant Phospholipase A1 (PLA1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB151Hu01 | Polyclonal Antibody to Phospholipase A1 (PLA1) | WB; IHC; ICC; IP; FCM |
| MAB151Hu22 | Monoclonal Antibody to Phospholipase A1 (PLA1) | WB; IHC; ICC; IP. | |
| PAB151Hu02 | Polyclonal Antibody to Phospholipase A1 (PLA1) | WB; IHC; ICC; IP; FCM | |
| LAB151Hu82 | FITC-Linked Monoclonal Antibody to Phospholipase A1 (PLA1) | WB; IHC; ICC; IF. | |
| LAB151Hu72 | Biotin-Linked Monoclonal Antibody to Phospholipase A1 (PLA1) | WB; IHC; ICC. | |
| LAB151Hu71 | Biotin-Linked Polyclonal Antibody to Phospholipase A1 (PLA1) | WB; IHC; ICC. | |
| Assay Kits | SEB151Hu | ELISA Kit for Phospholipase A1 (PLA1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Phospholipase A1 (PLA1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Phospholipase A1 (PLA1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Phospholipase A1 (PLA1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Phospholipase A1 (PLA1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Phospholipase A1 (PLA1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Phospholipase A1 (PLA1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Phospholipase A1 (PLA1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Phospholipase A1 (PLA1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Phospholipase A1 (PLA1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Phospholipase A1 (PLA1) | ELISA Kit Customized Service Offer |
- "nmd, a novel gene differentially expressed in human melanoma cell lines, encodes a new atypical member of the enzyme family of lipases."FEBS Lett. 404:82-86(1997) [PubMed] [Europe PMC] [Abstract]
- "An alternative splicing form of phosphatidylserine-specific phospholipase A1 that exhibits lysophosphatidylserine-specific lysophospholipase activity in humans."J. Biol. Chem. 274:11053-11059(1999) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 (PSPLA1)."J. Hum. Genet. 47:611-613(2002) [PubMed] [Europe PMC] [Abstract]