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Glia Maturation Factor Gamma (GMFg)

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Glia Maturation Factor Gamma (GMFg)
CCC B195
HGNC 4374
MGI 1927135
PubMed 17127212
RGD 620506
UniProt O60234
Wiki GMF

  • GMF-gamma was expressed as a 0.9-kb mRNA predominantly in lung, heart, and placenta. An additional low-abundance 1.2-kb transcript was detected in heart and skeletal muscle. Independently, Mao et al. (1998) identified a cDNA corresponding to GMF-gamma, which they referred to as a GMF-beta homolog, among a collection of cDNAs expressed in hematopoietic stem/progenitor cells.

  • GMF-gamma gene had been mapped to 19q13.2. This region is frequently deleted in human malignant gliomas and was thus suspected to harbor a glioma tumor suppressor gene. Given the putative role of GMF-gamma in cell differentiation and proliferation, and its map location, it became a candidate for said tumor suppressor gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB195Hu01 Recombinant Glia Maturation Factor Gamma (GMFg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB195Hu01 Polyclonal Antibody to Glia Maturation Factor Gamma (GMFg) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Glia Maturation Factor Gamma (GMFg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glia Maturation Factor Gamma (GMFg) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB195Mu01 Recombinant Glia Maturation Factor Gamma (GMFg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB195Mu01 Polyclonal Antibody to Glia Maturation Factor Gamma (GMFg) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Glia Maturation Factor Gamma (GMFg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glia Maturation Factor Gamma (GMFg) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glia Maturation Factor Gamma (GMFg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glia Maturation Factor Gamma (GMFg) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glia Maturation Factor Gamma (GMFg) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glia Maturation Factor Gamma (GMFg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glia Maturation Factor Gamma (GMFg) ELISA Kit Customized Service Offer
  1. "Isolation of novel human cDNA (hGMF-gamma) homologous to glia maturation factor-beta gene."Biochim. Biophys. Acta 1396:242-244(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The human glia maturation factor-gamma gene: genomic structure and mutation analysis in gliomas with chromosome 19q loss."Neurogenetics 2:163-166(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "The crystal structure of human glia maturation factor, gamma (GMFG)."Submitted (FEB-2010) to the PDB data bank