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Fibrinogen beta chain is found in humans and most other vertebrates with a similar system of blood coagulation. Fibrinogen beta chain is the beta component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots.
In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB215Mu01 | Recombinant Fibrinogen Beta Chain (FGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB215Mu02 | Recombinant Fibrinogen Beta Chain (FGB) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APB215Mu01 | Active Fibrinogen Beta Chain (FGB) | Cell culture; Activity Assays. | |
| Antibodies | PAB215Mu01 | Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC; IP. |
| PAB215Mu02 | Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB215Mu | ELISA Kit for Fibrinogen Beta Chain (FGB) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB215Ra01 | Recombinant Fibrinogen Beta Chain (FGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB215Ra02 | Recombinant Fibrinogen Beta Chain (FGB) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB215Ra01 | Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC; IP. |
| LAB215Ra71 | Biotin-Linked Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC. | |
| LAB215Ra81 | FITC-Linked Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC; IF. | |
| MAB215Ra21 | Monoclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC; IP. | |
| PAB215Ra02 | Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB215Ra | ELISA Kit for Fibrinogen Beta Chain (FGB) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB215Po01 | Recombinant Fibrinogen Beta Chain (FGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Fibrinogen Beta Chain (FGB) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Fibrinogen Beta Chain (FGB) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fibrinogen Beta Chain (FGB) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB215Bo01 | Recombinant Fibrinogen Beta Chain (FGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB215Bo01 | Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC; IP. |
| LAB215Bo71 | Biotin-Linked Polyclonal Antibody to Fibrinogen Beta Chain (FGB) | WB; IHC; ICC. | |
| Assay Kits | n/a | CLIA Kit for Fibrinogen Beta Chain (FGB) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fibrinogen Beta Chain (FGB) | ELISA Kit Customized Service Offer |
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- "Nucleotide sequences of the three genes coding for human fibrinogen."Adv. Exp. Med. Biol. 281:39-48(1990) [PubMed] [Europe PMC] [Abstract]
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- "Disulfide bridges in NH2-terminal part of human fibrinogen."Thromb. Res. 8:639-658(1976) [PubMed] [Europe PMC] [Abstract]
- "Studies on fibrinopeptides from primates."Acta Chem. Scand. 19:1788-1789(1965)
- "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]