Cluster Of Differentiation 56 (CD56)
[Edit]CD56; NCAM1; MSK39; N-CAM-1; NCAM; Neural Cell Adhesion Molecule
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Neural Cell Adhesion Molecule (NCAM, also the cluster of differentiation CD56) is a homophilic binding glycoprotein expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.
NCAM can be posttranslationally modified by the addition of polysialic acid (PSA) to the fifth Ig domain, which is thought to abrogate its homophilic binding properties and can lead to reduced cell adhesion important in cell migration and invasion. PSA has been shown to be critical in learning and memory. Removal of PSA from NCAM by the enzyme endoneuraminidase (EndoN) has been shown to abolish long-term potentiation (LTP) and long-term depression (LTD).
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Cluster Of Differentiation 56 (CD56) | Recombinant Protein Customized Service Offer |
| Antibodies | PAB225Mu01 | Polyclonal Antibody to Cluster Of Differentiation 56 (CD56) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Cluster Of Differentiation 56 (CD56) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Cluster Of Differentiation 56 (CD56) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Cluster Of Differentiation 56 (CD56) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Cluster Of Differentiation 56 (CD56) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Cluster Of Differentiation 56 (CD56) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Cluster Of Differentiation 56 (CD56) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Cluster Of Differentiation 56 (CD56) | ELISA Kit Customized Service Offer |
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