Fatty Acid Binding Protein 7, Brain (FABP7)

Fatty acid binding protein 7, brain (FABP7; also brain lipid binding protein, BLBP), is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism.

FABP7 is expressed, during development, in radial glia by the activation of Notch receptors. Reelin was shown to induce FABP7 expression in neural progenitor cells via Notch-1 activation. According to one study, FABP7 binds DHA with the highest affinity among all of the FABPs.FABP7 maps onto human chromosome 6q22.31, a schizophrenia linkage region corroborated by a meta-analysis..