≡

Cluster Of Differentiation 52 (CD52)

[Edit]

CDW52; HE5; CAMPATH-1 Antigen; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5

Cluster Of Differentiation 52 (CD52)
CCC B279
HGNC 1804
MGI 1346088
PubMed 9593475
UniProt P31358
Wiki CD52
CD52 is a protein present on the surface of mature lymphocytes. It also is found in monocytes and dendritic cells. It is a glycosylphosphatidylinositol (GPI)--anchored antigen expressed on the all lymphocytes as well as within the male genital tract.The CAMPATH-1 family of monoclonal antibodies recognize an antigen expressed on human lymphocytes and monocytes. The antigen is an unusually good target for complement-mediated attack and, for this reason, the IgM antibody, CAMPATH-1M, has been widely used for removal of T lymphocytes from donor bone marrow to prevent graft-vs-host disease. Because the target antigen is expressed in most cases of lymphoid malignancy, serotherapy of lymphoma and leukemia with CAMPATH-1 antibodies has also been attempted.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB279Hu01 Recombinant Cluster Of Differentiation 52 (CD52) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB279Hu01 Polyclonal Antibody to Cluster Of Differentiation 52 (CD52) WB; IHC; ICC; IP.
MAB279Hu21 Monoclonal Antibody to Cluster Of Differentiation 52 (CD52) WB; IHC; ICC; IP.
Assay Kits SEB279Hu ELISA Kit for Cluster Of Differentiation 52 (CD52) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cluster Of Differentiation 52 (CD52) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cluster Of Differentiation 52 (CD52) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cluster Of Differentiation 52 (CD52) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cluster Of Differentiation 52 (CD52) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cluster Of Differentiation 52 (CD52) ELISA Kit Customized Service Offer
  1. "Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone."Eur. J. Immunol. 21:1677-1684(1991) [PubMed] [Europe PMC] [Abstract]
  2. "A major mRNA of the human epididymal principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone."Mol. Reprod. Dev. 34:8-15(1993) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis."Biochem. J. 293:633-640(1993) [PubMed] [Europe PMC] [Abstract]