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Integrin Alpha 3 (ITGa3)

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CD49c; CD49-C; ITG-A3; GAP-B3; GAPB3; MSK18; VCA-2; VL3A; VLA3a; FRP-2; Galactoprotein B3; Alpha 3 Subunit Of VLA-3 Receptor; CD49 antigen-like family member C

Integrin Alpha 3 (ITGa3)
CCC B289
HGNC 6139
MGI 96602
PubMed 24371517
RGD 1310333
UniProt P26006
Wiki ITGA3
ITGA3 is an integrin alpha subunit. It makes up half of the α3β1 integrin duplex. ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins.
The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 ('VLA-3'), very common antigen 2 ('VCA-2'), extracellular matrix receptor 1 ('ECMR1'), and galactoprotein b3 ('GAPB3').

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Integrin Alpha 3 (ITGa3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Integrin Alpha 3 (ITGa3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Integrin Alpha 3 (ITGa3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Integrin Alpha 3 (ITGa3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrin Alpha 3 (ITGa3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB289Mu01 Recombinant Integrin Alpha 3 (ITGa3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB289Mu02 Recombinant Integrin Alpha 3 (ITGa3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB289Mu01 Polyclonal Antibody to Integrin Alpha 3 (ITGa3) WB; IHC; ICC; IP.
PAB289Mu02 Polyclonal Antibody to Integrin Alpha 3 (ITGa3) WB; IHC; ICC; IP.
Assay Kits SEB289Mu ELISA Kit for Integrin Alpha 3 (ITGa3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Integrin Alpha 3 (ITGa3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Integrin Alpha 3 (ITGa3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Integrin Alpha 3 (ITGa3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Integrin Alpha 3 (ITGa3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrin Alpha 3 (ITGa3) ELISA Kit Customized Service Offer
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  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
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  5. "Identification of human galactoprotein b3, an oncogenic transformation-induced membrane glycoprotein, as VLA-3 alpha subunit: the primary structure of human integrin alpha 3."J. Biochem. 109:659-665(1991) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular and biological characterization of fusion regulatory proteins (FRPs): anti-FRP mAbs induced HIV-mediated cell fusion via an integrin system."EMBO J. 13:2044-2055(1994) [PubMed] [Europe PMC] [Abstract]
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  11. "Palmitoylation supports assembly and function of integrin-tetraspanin complexes."J. Cell Biol. 167:1231-1240(2004) [PubMed] [Europe PMC] [Abstract]
  12. "NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin."Mol. Biol. Cell 15:3580-3590(2004) [PubMed] [Europe PMC] [Abstract]
  13. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  14. "Integrin alpha3 mutations with kidney, lung, and skin disease."N. Engl. J. Med. 366:1508-1514(2012) [PubMed] [Europe PMC] [Abstract]