V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS)
[Edit]Cfos; C-Fos; G0S7; Proto-oncogene c-Fos; G0/G1 Switch Regulatory Protein 7; Cellular oncogene fos
In molecular biology, c-Fos is a cellular proto-oncogene belonging to the immediate early gene family of transcription factors. c-Fos has a leucine-zipper DNA binding domain, and a transactivation domain at the C-terminus. Transcription of c-Fos is upregulated in response to many extracellular signals, e.g. growth factors. Additionally, phosphorylation by MAPK, PKA, PKC or cdc2 alters the activity and stability of c-Fos. Members of the Fos family dimerise with C-Jun to form the AP-1 transcription factor, which upregulates transcription of a diverse range of genes involved in everything from proliferation and differentiation to defense against invasion and cell damage. The viral homologue of c-Fos, v-Fos, is found in the retrovirus Finkel–Biskis–Jinkins murine osteogenic sarcoma virus.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB291Hu01 | Recombinant V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB291Hu01 | Polyclonal Antibody to V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | WB; IHC; ICC; IP. |
MAB291Hu22 | Monoclonal Antibody to V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | WB; IHC; ICC; IP. | |
Assay Kits | SEB291Hu | ELISA Kit for V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB291Ra01 | Recombinant V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB291Ra01 | Polyclonal Antibody to V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | WB; IHC; ICC; IP. |
MAB291Ra21 | Monoclonal Antibody to V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | WB; IHC; ICC; IP. | |
Assay Kits | SEB291Ra | ELISA Kit for V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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