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Actin Gamma 2, Smooth Muscle (ACTg2)

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ACT; ACT-G2; ACTA3; ACTE; ACTL3; ACTSG; Alpha-actin-3

Actin Gamma 2, Smooth Muscle (ACTg2)
CCC B344
HGNC 145
MGI 104589
PubMed 24337657
RGD 2027
UniProt P63267
Wiki ACTG2

Actin, gamma-enteric smooth muscle is a protein encoded by the ACTG2 gene.Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified.

The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB344Hu01 Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB344Hu51 Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) WB; IHC; ICC; IP.
PAB344Hu01 Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) WB; IHC
MAB344Hu21 Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) WB; IHC; ICC; IP.
Assay Kits SEB344Hu ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) Recombinant Protein Customized Service Offer
Antibodies PAB344Mu51 Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB344Ra01 Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB344Ra51 Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) ELISA Kit Customized Service Offer

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) Recombinant Protein Customized Service Offer
Antibodies PAB344Ov01 Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) ELISA Kit Customized Service Offer
  1. "The nucleotide sequence of a human smooth muscle (enteric type) gamma-actin cDNA."Nucleic Acids Res. 18:4263-4263(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Structure, chromosome location, and expression of the human smooth muscle (enteric type) gamma-actin gene: evolution of six human actin genes."Mol. Cell. Biol. 11:3296-3306(1991) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Segregation of a missense variant in enteric smooth muscle actin gamma-2 with autosomal dominant familial visceral myopathy."Gastroenterology 143:1482-1491(2012) [PubMed] [Europe PMC] [Abstract]
  7. "Familial visceral myopathy diagnosed by exome sequencing of a patient with chronic intestinal pseudo-obstruction."Endoscopy 46:533-537(2014) [PubMed] [Europe PMC] [Abstract]
  8. "De novo ACTG2 mutations cause congenital distended bladder, microcolon, and intestinal hypoperistalsis."Hum. Genet. 133:737-742(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Heterozygous de novo and inherited mutations in the smooth muscle actin (ACTG2) gene underlie megacystis-microcolon-intestinal hypoperistalsis syndrome." PLoS Genet. 10:E1004258-E1004258(2014) [PubMed] [Europe PMC] [Abstract]