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Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)

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CD309; FLK1; VEGFR; KDR; A Type III Receptor Tyrosine Kinase; Kinase Insert Domain Receptor; Kinase Insert Domain Receptor; Fetal Liver Kinase-1

Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)
CCC B367
HGNC 6307
MGI 96683
PubMed 23454747
RGD 2965
UniProt P35968
Wiki VEGFR2

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. 



Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB367Hu01 Recombinant Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Positive Control; Immunogen; SDS-PAGE; WB.
EPB367Hu61 Eukaryotic Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Positive Control; Immunogen; SDS-PAGE; WB.
APB367Hu61 Active Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Cell culture; Activity Assays.
APB367Hu01 Active Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Cell culture; Activity Assays.
Antibodies PAB367Hu01 Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
MAB367Hu22 Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
LAB367Hu71 Biotin-Linked Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC.
LAB367Hu81 FITC-Linked Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IF.
MAB367Hu21 Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
MAB367Hu23 Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
MAB367Hu26 Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
MAB367Hu24 Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
Assay Kits SEB367Hu ELISA Kit for Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Enzyme-linked immunosorbent assay for Antigen Detection.
HEB367Hu High Sensitive ELISA Kit for Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB367Mu01 Recombinant Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB367Mu02 Recombinant Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB367Mu01 Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
LAB367Mu71 Biotin-Linked Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC.
PAB367Mu02 Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
Assay Kits SEB367Mu ELISA Kit for Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB367Ra01 Recombinant Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB367Ra01 Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
LAB367Ra71 Biotin-Linked Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC.
MAB367Ra21 Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
Assay Kits SEB367Ra ELISA Kit for Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB367Po01 Recombinant Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB367Po01 Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
MAB367Po21 Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) WB; IHC; ICC; IP.
Assay Kits SEB367Po ELISA Kit for Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Polyclonal Antibody Customized Service Offer
Assay Kits SEB367Ov ELISA Kit for Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Enzyme-linked immunosorbent assay for Antigen Detection.
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