≡

Early B-Cell Factor 2 (EBF2)

[Edit]

COE2; Transcription factor COE2

Early B-Cell Factor 2 (EBF2)
CCC B423
HGNC 19090
MGI 894332
PubMed 23499423
RGD 1310805
UniProt Q9HAK2

EBF2 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors. Ebf2 was expressed in adipose tissue and in immature osteoblastic cells during mouse embryonic development. By assaying human embryonic kidney cells transfected with mouse Ebf2,  Ebf2 could activate transcription of a reporter gene from a promoter containing Olf/EBF binding sites.

Ebf2 was induced about 5-fold during the differentiation of mouse osteoblasts. Ebf2 bound to sequences in the osteoprotegerin gene (OPG) and transactivated the Opg promoter in synergy with the Wnt -responsive Lef1/ beta-catenin  pathway.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB423Hu01 Recombinant Early B-Cell Factor 2 (EBF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB423Hu01 Polyclonal Antibody to Early B-Cell Factor 2 (EBF2) WB
Assay Kits n/a CLIA Kit for Early B-Cell Factor 2 (EBF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Early B-Cell Factor 2 (EBF2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Early B-Cell Factor 2 (EBF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Early B-Cell Factor 2 (EBF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Early B-Cell Factor 2 (EBF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Early B-Cell Factor 2 (EBF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Early B-Cell Factor 2 (EBF2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Early B-Cell Factor 2 (EBF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Early B-Cell Factor 2 (EBF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Early B-Cell Factor 2 (EBF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Early B-Cell Factor 2 (EBF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Early B-Cell Factor 2 (EBF2) ELISA Kit Customized Service Offer
  1. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]