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Lysosomal Associated Membrane Protein 1 (LAMP1)

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CD107-A; CD107a; LAMPA; LGP120; Lysosome-associated membrane protein 1; CD107 antigen-like family member A

Lysosomal Associated Membrane Protein 1 (LAMP1)
CCC B441
HGNC 6499
MGI 96745
PubMed 23632890
RGD 2989
UniProt P11279
Wiki LAMP1

Lysosomal-associated membrane protein 1 (LAMP1) also known as CD107a (Cluster of Differentiation 107a) , The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.

The deduced amino acid sequence demonstrated that the rat LGP120 contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment, and a short (11 amino acid) cytosolic tail. LGP120 showed similarity to 2 other lysosomal membrane proteins and showed a high degree of conservation in domain organization and primary structure with the proteins in other species.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB441Hu01 Recombinant Lysosomal Associated Membrane Protein 1 (LAMP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB441Hu01 Polyclonal Antibody to Lysosomal Associated Membrane Protein 1 (LAMP1) WB; IHC; ICC; IP.
MAB441Hu21 Monoclonal Antibody to Lysosomal Associated Membrane Protein 1 (LAMP1) WB; IHC; ICC; IP.
Assay Kits SEB441Hu ELISA Kit for Lysosomal Associated Membrane Protein 1 (LAMP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysosomal Associated Membrane Protein 1 (LAMP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysosomal Associated Membrane Protein 1 (LAMP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysosomal Associated Membrane Protein 1 (LAMP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysosomal Associated Membrane Protein 1 (LAMP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysosomal Associated Membrane Protein 1 (LAMP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysosomal Associated Membrane Protein 1 (LAMP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysosomal Associated Membrane Protein 1 (LAMP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysosomal Associated Membrane Protein 1 (LAMP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysosomal Associated Membrane Protein 1 (LAMP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysosomal Associated Membrane Protein 1 (LAMP1) ELISA Kit Customized Service Offer
  1. "Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences."J. Biol. Chem. 263:18920-18928(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Purification and characterization of human lysosomal membrane glycoproteins."Arch. Biochem. Biophys. 268:360-378(1989) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000."Proc. Natl. Acad. Sci. U.S.A. 85:3743-3747(1988) [PubMed] [Europe PMC] [Abstract]
  7. "The genes of major lysosomal membrane glycoproteins, lamp-1 and lamp-2. 5'-flanking sequence of lamp-2 gene and comparison of exon organization in two genes."J. Biol. Chem. 268:9014-9022(1993) [PubMed] [Europe PMC] [Abstract]
  8. "Structure of human lysosomal membrane glycoprotein 1. Assignment of disulfide bonds and visualization of its domain arrangement."J. Biol. Chem. 264:20526-20531(1989) [PubMed] [Europe PMC] [Abstract]
  9. "The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Localization on the peptide backbones."J. Biol. Chem. 265:20488-20495(1990) [PubMed] [Europe PMC] [Abstract]
  10. "Assignment of O-glycan attachment sites to the hinge-like regions of human lysosomal membrane glycoproteins lamp-1 and lamp-2."Arch. Biochem. Biophys. 304:65-73(1993) [PubMed] [Europe PMC] [Abstract]
  11. "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry."Nat. Biotechnol. 21:660-666(2003) [PubMed] [Europe PMC] [Abstract]
  12. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  13. "The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments."Mol. Biol. Cell 16:5480-5492(2005) [PubMed] [Europe PMC] [Abstract]
  14. "Integral and associated lysosomal membrane proteins."Traffic 8:1676-1686(2007) [PubMed] [Europe PMC] [Abstract]
  15. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  18. "Virus entry. Lassa virus entry requires a trigger-induced receptor switch."Science 344:1506-1510(2014) [PubMed] [Europe PMC] [Abstract]