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Octamer Binding Transcription Factor 1 (OCT1)

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POU2F1; OTF1; NF-A1; POU Domain,Class 2,Transcription Factor 1; Octamer-binding transcription factor 1

Octamer Binding Transcription Factor 1 (OCT1)
CCC B553
HGNC 9212
MGI 101898
PubMed 20935455
UniProt P14859
Wiki POU2F1

POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is additionally conferred at the dimerization level. Tomilin et al. (2000) found that the POU dimer from the OCT1 gene formed on the palindromic OCT factor recognition element, or PORE (ATTTGAAATGCAAAT), could recruit the transcriptional coactivator OBF1, whereas POU dimers formed on the consensus MORE or on MOREs from immunoglobulin heavy chain promoters failed to interact. An interaction with OBF1 was precluded since the same OCT1 residues that form the MORE dimerization interface are also used for OBF1/OCT1 interactions on the PORE.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB553Hu01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB553Hu01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB553Mu01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB553Mu01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) ELISA Kit Customized Service Offer
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