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Glucocorticoid Receptor (GR)

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GCCR; GCR; NR3C1; GRL; NR3-C1; Nuclear Receptor Subfamily 3, Group C, Member 1

Glucocorticoid Receptor (GR)
CCC B608
HGNC 7978
MGI 95824
PubMed 12754700
RGD 2741
UniProt P04150
Wiki NR3C1

The GR is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins.
The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB608Hu01 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB608Hu02 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB608Hu03 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB608Hu04 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB608Hu06 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
APB608Hu01 Active Glucocorticoid Receptor (GR) Cell culture; Activity Assays.
Antibodies PAB608Hu01 Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
MAB608Hu22 Monoclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
LAB608Hu71 Biotin-Linked Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC.
PAB608Hu02 Polyclonal Antibody to Glucocorticoid Receptor (GR) WB,IHC
PAB608Hu03 Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
MAB608Hu21 Monoclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
Assay Kits SEB608Hu ELISA Kit for Glucocorticoid Receptor (GR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB608Mu02 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB608Mu01 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB608Mu01 Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
PAB608Mu02 Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Glucocorticoid Receptor (GR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glucocorticoid Receptor (GR) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB608Ra01 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB608Ra02 Recombinant Glucocorticoid Receptor (GR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB608Ra01 Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
LAB608Ra71 Biotin-Linked Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC.
MAB608Ra21 Monoclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
PAB608Ra02 Polyclonal Antibody to Glucocorticoid Receptor (GR) WB; IHC; ICC; IP.
Assay Kits SEB608Ra ELISA Kit for Glucocorticoid Receptor (GR) Enzyme-linked immunosorbent assay for Antigen Detection.
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