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Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1)

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N-AChRB1; NAChRB1; CMS2A; SCCMS; ACHRB; CHRNB; CMS1D; N-AChR-B1; Neuronal Acetylcholine Receptor Beta 1; Acetylcholine receptor subunit beta

Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1)
CCC B648
HGNC 1961
MGI 87890
PubMed 9307231
RGD 2349
UniProt P11230
Wiki CHRNB1

Acetylcholine receptor subunit beta is a protein encoded by the CHRNB1 gene.The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor.

The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB648Ra01 Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB648Ra01 Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) WB; IHC; ICC; IP.
MAB648Ra21 Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) WB; IHC; ICC; IP.
Assay Kits SEB648Ra ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Nucleotide sequence of human muscle acetylcholine receptor beta-subunit."Nucleic Acids Res. 17:4391-4391(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A beta-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome."Ann. Neurol. 39:712-723(1996) [PubMed] [Europe PMC] [Abstract]
  6. "New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome."Hum. Mol. Genet. 5:1217-1227(1996) [PubMed] [Europe PMC] [Abstract]
  7. "Mutation causing congenital myasthenia reveals acetylcholine receptor beta/delta subunit interaction essential for assembly."J. Clin. Invest. 104:1403-1410(1999) [PubMed] [Europe PMC] [Abstract]