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TATA Box Binding Protein Associated Factor 2 (TAF2)

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CIF150; TAF2B; TAFII150; TAF2 RNA Polymerase II; Transcription Initiation Factor TFIID Subunit 2; 150 kDa cofactor of initiator function RNA polymerase II TBP-associated factor B

TATA Box Binding Protein Associated Factor 2 (TAF2)
CCC B676
HGNC 11536
MGI 2443028
PubMed 24084144
RGD 621487
UniProt Q6P1X5
Wiki TAF2

Transcription initiation factor TFIID subunit 2 is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.

TFIID is composed of the TATA binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB676Hu01 Recombinant TATA Box Binding Protein Associated Factor 2 (TAF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB676Hu01 Polyclonal Antibody to TATA Box Binding Protein Associated Factor 2 (TAF2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 2 (TAF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 2 (TAF2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 2 (TAF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 2 (TAF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 2 (TAF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 2 (TAF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 2 (TAF2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 2 (TAF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 2 (TAF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 2 (TAF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 2 (TAF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 2 (TAF2) ELISA Kit Customized Service Offer
  1. "CIF150, a human cofactor for transcription factor IID-dependent initiator function."Mol. Cell. Biol. 18:233-239(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex."Mol. Cell. Biol. 18:6571-6583(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis."Proteomics 3:217-223(2003) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Deep sequencing reveals 50 novel genes for recessive cognitive disorders." Nature 478:57-63(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Microcephaly thin corpus callosum intellectual disability syndrome caused by mutated TAF2."Pediatr. Neurol. 49:411-417(2013) [PubMed] [Europe PMC] [Abstract]