Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)

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CD256; APRIL; TALL2; TRDL1; ZTNF2; A Proliferation Inducing Ligand; TNF And APOL Related Leukocyte Expressed Ligand 2; TNF-Related Death Ligand 1

Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)

Tumor necrosis factor ligand superfamily member 13 is a member of the tumor necrosis factor (TNF) ligand family. Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.

This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB750Hu01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB750Hu01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
MAB750Hu22 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
LAB750Hu71 Biotin-Linked Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC.
LAB750Hu81 FITC-Linked Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IF.
Assay Kits SEB750Hu ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB750Mu01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Positive Control; Immunogen; SDS-PAGE; WB.
RPB750Mu02 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB750Mu01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
LAB750Mu71 Biotin-Linked Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC.
LAB750Mu81 FITC-Linked Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IF.
PAB750Mu02 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
Assay Kits SEB750Mu ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB750Ra01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB750Ra01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
MAB750Ra21 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
Assay Kits SEB750Ra ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB750Si01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB750Si01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB750Ca01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB750Ca01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
LAB750Ca71 Biotin-Linked Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC.
MAB750Ca21 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB750Bo01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB750Bo01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) ELISA Kit Customized Service Offer
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  2. "TALL-1 is a novel member of the TNF family that is down-regulated by mitogens."J. Leukoc. Biol. 65:680-683(1999) [PubMed] [Europe PMC] [Abstract]
  3. "APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death."Cancer Res. 60:1021-1027(2000) [PubMed] [Europe PMC] [Abstract]
  4. "An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein."EMBO J. 21:5711-5720(2002) [PubMed] [Europe PMC] [Abstract]
  5. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  7. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  9. "APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity."Nat. Immunol. 1:252-256(2000) [PubMed] [Europe PMC] [Abstract]
  10. "Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase."EMBO Rep. 2:945-951(2001) [PubMed] [Europe PMC] [Abstract]