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Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1)

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CD314; KLR-K1; KLR; NKG2-D; NKG2-D Type II Integral Membrane Protein; NK cell receptor D; NKG2-D-activating NK receptor

Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1)
CCC B765
HGNC 18788
MGI 1196250
PubMed 19140827
RGD 3180
UniProt P26718
Wiki NKG2D

NKG2-D type II integral membrane protein is a protein encoded by the KLRK1 gene.KLRK1 has also been designated as CD314 (cluster of differentiation 314).Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity.

NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. D12S2489E is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB765Hu01 Recombinant Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB765Hu01 Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) WB; IHC; ICC; IP.
MAB765Hu21 Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB765Mu01 Recombinant Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB765Mu01 Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB765Ra01 Recombinant Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB765Ra01 Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily K, Member 1 (KLRK1) ELISA Kit Customized Service Offer
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  14. "The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure."Proc. Natl. Acad. Sci. U.S.A. 102:7641-7646(2005) [PubMed] [Europe PMC] [Abstract]
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  20. "Symmetry recognizing asymmetry: analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and MHC class I-like ligands."Structure 11:411-422(2003) [PubMed] [Europe PMC] [Abstract]