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Junctional Adhesion Molecule 1 (JAM1)

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CD321; F11R; KAT; JAM-A; JAMA; JCAM; PAM1; Coagulation Factor XI Receptor; Platelet F11 receptor; Platelet adhesion molecule 1

Junctional Adhesion Molecule 1 (JAM1)
CCC B782
HGNC 14685
MGI 1321398
PubMed 15065765
RGD 621842
UniProt Q9Y624
Wiki F11_receptor

F11 receptor, also known as F11R  has also been designated as CD321 (cluster of differentiation 321). Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.

The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple transcript variants encoding two different isoforms have been found for this gene .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB782Hu01 Recombinant Junctional Adhesion Molecule 1 (JAM1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB782Hu01 Polyclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) WB; IHC; ICC; IP.
MAB782Hu22 Monoclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) WB; IHC; ICC; IP.
MAB782Hu21 Monoclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) WB; IHC; ICC; IP.
MAB782Hu23 Monoclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) WB; IHC; ICC; IP.
Assay Kits SEB782Hu ELISA Kit for Junctional Adhesion Molecule 1 (JAM1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB782Mu01 Recombinant Junctional Adhesion Molecule 1 (JAM1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Junctional Adhesion Molecule 1 (JAM1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Junctional Adhesion Molecule 1 (JAM1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB782Ra01 Recombinant Junctional Adhesion Molecule 1 (JAM1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Junctional Adhesion Molecule 1 (JAM1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Junctional Adhesion Molecule 1 (JAM1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Junctional Adhesion Molecule 1 (JAM1) ELISA Kit Customized Service Offer
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  21. "Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding."Proc. Natl. Acad. Sci. U.S.A. 100:5366-5371(2003) [PubMed] [Europe PMC] [Abstract]