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Junctional Adhesion Molecule 2 (JAM2)

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CD322; JAM-B; JAMB; VE-JAM; VEJAM; Junctional adhesion molecule B; Vascular endothelial junction-associated molecule

Junctional Adhesion Molecule 2 (JAM2)
CCC B783
HGNC 14686
MGI 1933820
PubMed 12239159
RGD 1561692
UniProt P57087
Wiki JAM2

Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene.Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.

The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB783Hu01 Recombinant Junctional Adhesion Molecule 2 (JAM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB783Hu01 Polyclonal Antibody to Junctional Adhesion Molecule 2 (JAM2) WB; IHC; ICC; IP.
MAB783Hu21 Monoclonal Antibody to Junctional Adhesion Molecule 2 (JAM2) WB; IHC; ICC; IP.
Assay Kits SEB783Hu ELISA Kit for Junctional Adhesion Molecule 2 (JAM2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Junctional Adhesion Molecule 2 (JAM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Junctional Adhesion Molecule 2 (JAM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Junctional Adhesion Molecule 2 (JAM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Junctional Adhesion Molecule 2 (JAM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Junctional Adhesion Molecule 2 (JAM2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB783Ra01 Recombinant Junctional Adhesion Molecule 2 (JAM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Junctional Adhesion Molecule 2 (JAM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Junctional Adhesion Molecule 2 (JAM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Junctional Adhesion Molecule 2 (JAM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Junctional Adhesion Molecule 2 (JAM2) ELISA Kit Customized Service Offer
  1. "Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells."J. Biol. Chem. 275:19139-19145(2000) [PubMed] [Europe PMC] [Abstract]
  2. "A novel protein with homology to the junctional adhesion molecule: Characterization of leukocyte interactions."J. Biol. Chem. 275:34750-34756(2000) [PubMed] [Europe PMC] [Abstract]
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  8. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor."J. Biol. Chem. 276:45826-45832(2001) [PubMed] [Europe PMC] [Abstract]
  10. "Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response."Trends Immunol. 24:327-334(2003) [PubMed] [Europe PMC] [Abstract]
  11. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]