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Tumor Associated Calcium Signal Transducer 2 (TACSTD2)

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EGP-1; M1S1; TROP2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1; Cell surface glycoprotein Trop-2

Tumor Associated Calcium Signal Transducer 2 (TACSTD2)
CCC B787
HGNC 11530
MGI 1861606
PubMed 24651436
RGD 1359498
UniProt P09758
Wiki TACSTD2

Tumor-associated calcium signal transducer 2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.

The GA733 proteins were found to contain sequences homologous to a repeat unit occurring 10 times in thyroglobulin and once in the HLA-DR-associated invariant chain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB787Hu01 Recombinant Tumor Associated Calcium Signal Transducer 2 (TACSTD2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB787Hu01 Polyclonal Antibody to Tumor Associated Calcium Signal Transducer 2 (TACSTD2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Associated Calcium Signal Transducer 2 (TACSTD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Associated Calcium Signal Transducer 2 (TACSTD2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB787Mu01 Recombinant Tumor Associated Calcium Signal Transducer 2 (TACSTD2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB787Mu01 Polyclonal Antibody to Tumor Associated Calcium Signal Transducer 2 (TACSTD2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Associated Calcium Signal Transducer 2 (TACSTD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Associated Calcium Signal Transducer 2 (TACSTD2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Associated Calcium Signal Transducer 2 (TACSTD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Associated Calcium Signal Transducer 2 (TACSTD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Associated Calcium Signal Transducer 2 (TACSTD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Associated Calcium Signal Transducer 2 (TACSTD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Associated Calcium Signal Transducer 2 (TACSTD2) ELISA Kit Customized Service Offer
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  6. "Identification of the gene responsible for gelatinous drop-like corneal dystrophy."Nat. Genet. 21:420-423(1999) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "A novel mutation in the M1S1 gene responsible for gelatinous droplike corneal dystrophy."Invest. Ophthalmol. Vis. Sci. 42:2762-2764(2001) [PubMed] [Europe PMC] [Abstract]