Interleukin 6 Receptor (IL6R)
[Edit]CD126; gp80; IL6R; IL-6R-1; IL-6R-Alpha; IL6RA; IL-6 receptor subunit alpha; Membrane glycoprotein 80
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Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. In melanocytic cells IL6R gene expression may be regulated by MITF.
The IL6 receptor is a protein complex consisting of a IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit also shared by many other cytokines.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB815Hu01 | Recombinant Interleukin 6 Receptor (IL6R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPB815Hu61 | Eukaryotic Interleukin 6 Receptor (IL6R) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APB815Hu61 | Active Interleukin 6 Receptor (IL6R) | Cell culture; Activity Assays. | |
| Antibodies | PAB815Hu01 | Polyclonal Antibody to Interleukin 6 Receptor (IL6R) | WB; IHC; ICC; IP. |
| MAB815Hu22 | Monoclonal Antibody to Interleukin 6 Receptor (IL6R) | WB; IHC; ICC; IP. | |
| LAB815Hu71 | Biotin-Linked Polyclonal Antibody to Interleukin 6 Receptor (IL6R) | WB; IHC; ICC. | |
| Assay Kits | SEB815Hu | ELISA Kit for Interleukin 6 Receptor (IL6R) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB815Mu01 | Recombinant Interleukin 6 Receptor (IL6R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB815Mu02 | Recombinant Interleukin 6 Receptor (IL6R) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APB815Mu02 | Active Interleukin 6 Receptor (IL6R) | Cell culture; Activity Assays. | |
| Antibodies | PAB815Mu01 | Polyclonal Antibody to Interleukin 6 Receptor (IL6R) | WB; IHC; ICC; IP. |
| PAB815Mu02 | Polyclonal Antibody to Interleukin 6 Receptor (IL6R) | WB; IHC; ICC; IP. | |
| LAB815Mu71 | Biotin-Linked Polyclonal Antibody to Interleukin 6 Receptor (IL6R) | WB; IHC; ICC. | |
| Assay Kits | SEB815Mu | ELISA Kit for Interleukin 6 Receptor (IL6R) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
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