Apolipoprotein C4 (APOC4)

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Apo-C4; Apolipoprotein C-IV

Apolipoprotein C4 (APOC4)
Allan et al. (1995) identified and characterized a previously unreported human gene located within the previously known cluster of apolipoprotein genes on chromosome 19: APOE , APOC1 , and APOC2 . On the basis of its location and its properties, the new gene was designated APOC4. Nucleotide sequence analysis of genomic DNA and liver cDNA clones revealed a 3.3-kb gene consisting of 3 exons and 2 introns. Its 3-prime terminus lies 555 bp upstream of APOC2, giving the 2 genes the same transcriptional orientation.
The promoter of the APOC4 lacks a typical TATA box, consistent with an apparent heterogeneity in transcription start sites. RNase protection analysis indicated relatively low apoC-IV mRNA levels in human liver, compared to apoC-II mRNA levels.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB828Hu01 Recombinant Apolipoprotein C4 (APOC4) Positive Control; Immunogen; SDS-PAGE; WB.
RPB828Hu02 Recombinant Apolipoprotein C4 (APOC4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB828Hu01 Polyclonal Antibody to Apolipoprotein C4 (APOC4) WB; IHC; ICC; IP.
MAB828Hu22 Monoclonal Antibody to Apolipoprotein C4 (APOC4) WB; IHC; ICC; IP.
Assay Kits SEB828Hu ELISA Kit for Apolipoprotein C4 (APOC4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB828Mu01 Recombinant Apolipoprotein C4 (APOC4) Positive Control; Immunogen; SDS-PAGE; WB.
CPB828Mu21 OVA Conjugated Apolipoprotein C4 (APOC4) Immunogen; SDS-PAGE; WB.
Antibodies PAB828Mu01 Polyclonal Antibody to Apolipoprotein C4 (APOC4) WB; IHC; ICC; IP.
PAB828Mu08 Polyclonal Antibody to Apolipoprotein C4 (APOC4) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Apolipoprotein C4 (APOC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apolipoprotein C4 (APOC4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins EPB828Ra61 Eukaryotic Apolipoprotein C4 (APOC4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Apolipoprotein C4 (APOC4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Apolipoprotein C4 (APOC4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Apolipoprotein C4 (APOC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apolipoprotein C4 (APOC4) ELISA Kit Customized Service Offer
  1. "Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-I, and C-II gene locus."Genomics 28:291-300(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence variation in human apolipoprotein C4 gene and its effect on plasma lipid profile."Atherosclerosis 152:193-201(2000) [PubMed] [Europe PMC] [Abstract]
  6. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]