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Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2)

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CD48; BLAST; BLAST1; MEM-102; BCM1; HCD48; MCD48; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2

Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2)
CCC B843
HGNC 1683
MGI 88339
PubMed 1693656
RGD 620620
UniProt P09326
Wiki CD48

  • BLAST1 is the designation used for an activation-associated cell surface glycoprotein of 40 to 45 kD expressed primarily in mitogen-stimulated human lymphocytes. The protein sequence predicted by the cDNA encoding BLAST1 indicates that BLAST1 is a member of the immunoglobulin supergene family. Yokoyama (1991) identified the BLAST1 activation/adhesion molecule as CD48.

  • Using recombinant human natural killer (NK) cell-activating ligand 2B4 fused to domains 3 and 4 of rodent Cd4  and flow cytometric analysis, Brown et al. (1998) demonstrated that CD48 binds to 2B4. BIAcore surface plasmon resonance analysis showed that the affinity of CD48 for 2B4 is approximately 10-fold higher than that shown for CD48 and CD2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB843Hu01 Recombinant Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB843Hu01 Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) WB; IHC; ICC; IP.
Assay Kits SEB843Hu ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB843Mu01 Recombinant Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB843Mu01 Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB843Ra01 Recombinant Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB843Ra01 Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) ELISA Kit Customized Service Offer
  1. "The isolation of cDNA clones for CD48."Immunogenetics 33:113-117(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1."Immunogenetics 33:108-112(1991) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular cloning of the lymphocyte activation marker Blast-1."EMBO J. 6:3695-3701(1987) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Characterization of the Epstein-Barr virus-inducible gene encoding the human leukocyte adhesion and activation antigen BLAST-1 (CD48)."Mol. Cell. Biol. 11:1614-1623(1991) [PubMed] [Europe PMC] [Abstract]
  7. "TCT.1, a target molecule for gamma/delta T cells, is encoded by an immunoglobulin superfamily gene (Blast-1) located in the CD1 region of human chromosome 1."J. Exp. Med. 173:1339-1344(1991) [PubMed] [Europe PMC] [Abstract]
  8. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Solution structure of the first Ig-like domain from human CD48 antigen."Submitted (AUG-2007) to the PDB data bank